关于他汀类药物诱发肌病的机制 - Suppr

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On the mechanisms of statin-induced myopathy.

作者信息

Laaksonen Reijo

机构信息

Tampere University Hospital, Tampere, Finland.

出版信息

Clin Pharmacol Ther. 2006 Jun;79(6):529-31. doi: 10.1016/j.clpt.2006.02.013. Epub 2006 May 2.

DOI:10.1016/j.clpt.2006.02.013

PMID:16765140

Abstract

摘要

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On the mechanisms of statin-induced myopathy.关于他汀类药物诱发肌病的机制

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[Statin-induced muscular problems are underestimated].他汀类药物引起的肌肉问题被低估了。

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Statin myopathies: pathophysiologic and clinical perspectives.他汀类药物所致肌病：病理生理学与临床视角

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The effects of CoQ10 supplements on patients taking statin drugs.辅酶Q10补充剂对服用他汀类药物患者的影响。

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Potential adverse effects of statins on muscle.他汀类药物对肌肉的潜在不良反应。

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Succinylcholine should be avoided in patients on statin therapy.正在接受他汀类药物治疗的患者应避免使用琥珀酰胆碱。

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Abnormal splicing of NEDD4 in myotonic dystrophy type 2: possible link to statin adverse reactions.强直性肌营养不良2型中NEDD4的异常剪接：与他汀类药物不良反应的可能联系。

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Genet Med. 2014 Nov;16(11):810-9. doi: 10.1038/gim.2014.41. Epub 2014 May 8.

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Br J Clin Pharmacol. 2014 Sep;78(3):649-59. doi: 10.1111/bcp.12367.

UGT1A1*28 is associated with decreased systemic exposure of atorvastatin lactone.UGT1A1*28 与阿托伐他汀内酯的全身暴露减少有关。

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