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他汀类药物引起的肌病表现为两名脊椎按摩治疗患者出现的机械性肌肉骨骼疼痛。

Statin induced myopathy presenting as mechanical musculoskeletal pain observed in two chiropractic patients.

作者信息

Rodine Robert J, Tibbles Anthony C, Kim Peter Sy, Alikhan Neetan

机构信息

Associate Professor, Director of Clinical Education and Patient Care, Canadian Memorial Chiropractic College, 6100 Leslie Street, Toronto, Ontario, M2H 3J1. Tel: 416-482-2340.

出版信息

J Can Chiropr Assoc. 2010 Mar;54(1):43-51.

Abstract

Lipid lowering drugs, such as statins, are commonly used to treat approximately 10 million Canadians affected by hypercholesterolemia. The most commonly experienced side-effect of statin medication is muscle pain. Statin induced myopathy consists of a spectrum of myopathic disorders ranging from mild myalgia to fatal rhabdomyolysis. The following is a presentation of 2 cases of statin induced myopathy in patients presenting in a chiropractic setting. In addition, discussion will surround the mechanism, predisposing risk factors and frequency of statin induced myopathy while highlighting the role that chiropractors and other manual therapists may play in its recognition and management.

摘要

降脂药物,如他汀类药物,通常用于治疗约1000万受高胆固醇血症影响的加拿大人。他汀类药物最常见的副作用是肌肉疼痛。他汀类药物引起的肌病包括一系列肌病性疾病,从轻症肌痛到致命的横纹肌溶解。以下介绍2例在脊椎按摩治疗环境中出现的他汀类药物引起的肌病病例。此外,还将讨论他汀类药物引起的肌病的机制、易感风险因素和发生率,同时强调脊椎按摩师和其他手法治疗师在其识别和管理中可能发挥的作用。

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本文引用的文献

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Prevalence of musculoskeletal pain and statin use.肌肉骨骼疼痛的患病率和他汀类药物的使用情况。
J Gen Intern Med. 2008 Aug;23(8):1182-6. doi: 10.1007/s11606-008-0636-7. Epub 2008 May 1.

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