Parmar Pragya, Salman Amjad, Kaliamurthy Jayaraman, Prasanth Duraisamy Aravind, Thomas Philip Aloysius, Jesudasan Christdas Arul Nelson
Institute of Ophthalmology, Joseph Eye Hospital, Tamil Nadu, India.
Am J Ophthalmol. 2006 Jun;141(6):1160-1. doi: 10.1016/j.ajo.2006.01.046.
To compare the per-operative contamination of anterior chamber among eyes undergoing manual small-incision cataract surgery (MSICS) and phacoemulsification (PE).
Prospective, randomized, interventional clinical trial.
In this study conducted at a tertiary-care center in southern India, 150 eyes undergoing cataract surgery were randomly allocated to undergo MSICS (group A, 75 eyes) and PE (group B, 75 eyes). Aqueous samples were taken before and at the end of surgery. Collected material was subjected to standard microbiological analysis. No preoperative antibiotics were used, but povidone-iodine 5% drops were instilled before surgery. Main outcome measures studied were the incidence of positive cultures in aqueous samples obtained from eyes in both groups.
The incidence of anterior chamber contamination in the MSICS group (4%) did not significantly differ from the PE group (2.7%; P = .65).
Incidence of anterior chamber contamination is similar among eyes undergoing MSICS and PE.
比较接受手法小切口白内障手术（MSICS）和超声乳化白内障吸除术（PE）的患者术中前房污染情况。
前瞻性、随机、干预性临床试验。
在印度南部一家三级医疗中心进行的本研究中，150例接受白内障手术的患者被随机分为接受MSICS组（A组，75只眼）和PE组（B组，75只眼）。在手术前和手术结束时采集房水样本。对采集的样本进行标准微生物学分析。术前未使用抗生素，但术前滴入5%聚维酮碘滴眼液。研究的主要观察指标是两组患者眼内房水样本培养阳性的发生率。
MSICS组前房污染发生率（4%）与PE组（2.7%；P = 0.65）无显著差异。
接受MSICS和PE的患者前房污染发生率相似。
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