Gimbel H V, Sun R, DeBroff B M, Yang H M
Gimbel Eye Centre, Calgary, Alberta, Canada.
Ophthalmic Surg Lasers. 1996 Feb;27(2):121-6.
A randomized, prospective study was undertaken to evaluate the incidence of positive cultures in the anterior chamber following cataract surgery when using intracameral gentamicin compared with no antibiotic.
A total of 97 patients were enrolled-- 48 receiving gentamicin in the irrigating solution and 49 receiving no intracameral antibiotics (control group). Each cataract extraction was accomplished by phacoemulsification followed by intraocular lens implantation. At the end of surgery, o.1 ml of anterior chamber fluid from each case was collected and cultured.
All cultures were negative in the group receiving gentamicin. However, one positive culture occurred in the control group. There was no significant difference in the positive culture rate between the two groups (P = .52).
This study suggests that cataract extraction with phacoemulsification and intraocular lens implantation has greatly reduced the incidence of bacterial contamination of anterior chamber fluid, with or without the use of intracameral antibiotic.
开展一项随机、前瞻性研究，以评估白内障手术中使用前房内庆大霉素与不使用抗生素相比，前房培养阳性的发生率。
共纳入97例患者，其中48例在灌注液中使用庆大霉素，49例未使用前房内抗生素（对照组）。每例白内障摘除均通过超声乳化术完成，随后植入人工晶状体。手术结束时，收集每例患者0.1ml前房液进行培养。
接受庆大霉素治疗的组所有培养结果均为阴性。然而，对照组出现1例培养阳性。两组之间的培养阳性率无显著差异（P = 0.52）。
本研究表明，超声乳化白内障摘除联合人工晶状体植入术极大地降低了前房液细菌污染的发生率，无论是否使用前房内抗生素。
