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分娩期窒息与脑瘫:有关联吗?

Intrapartum asphyxia and cerebral palsy: is there a link?

作者信息

Perlman Jeffrey M

机构信息

Department of Pediatrics, Weill Cornell Medical Center, New York, NY 10021, USA.

出版信息

Clin Perinatol. 2006 Jun;33(2):335-53. doi: 10.1016/j.clp.2006.03.004.

DOI:10.1016/j.clp.2006.03.004
PMID:16765728
Abstract

Perinatal hypoxic-ischemic cerebral injury, secondary to interruption of placental blood flow that results in cerebral palsy (CP), is a rare event. The ability to link an intrapartum event to subsequent CP should include a history of a sentinel event during labor, followed by the delivery of a depressed acidemic infant, and the subsequent evolution of neonatal encephalopathy, systemic organ injury, and acute neuroimaging abnormalities.

摘要

围产期缺氧缺血性脑损伤继发于胎盘血流中断,可导致脑瘫(CP),这是一种罕见事件。将产时事件与随后的脑瘫联系起来的能力应包括分娩时有一个标志性事件的病史,随后娩出一个有酸中毒的低活力婴儿,以及随后新生儿脑病、全身器官损伤和急性神经影像学异常的演变过程。

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