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血液透析患者股骨颈骨折后的预期寿命和功能预后

Life expectancy and functional prognosis after femoral neck fractures in hemodialysis patients.

作者信息

Sakabe Tomoya, Imai Ryo, Murata Hiroaki, Fujioka Mikihiro, Iwamoto Noriyuki, Ono Toshihiko, Kubo Toshikazu

机构信息

Department of Orthopaedics, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, 465 Kawaramachi-Hirokoji, Kyoto, 602-8566, Japan.

出版信息

J Orthop Trauma. 2006 May;20(5):330-6. doi: 10.1097/00005131-200605000-00006.

Abstract

OBJECTIVES

To identify whether differences exist in the outcomes between patients undergoing hemodialysis and elderly nonhemodialysis patients with a femoral neck fracture.

DESIGN

Retrospective review.

SETTING

Level 1 trauma center.

PATIENTS/INTERVENTIONS: A total of 71 femoral neck fractures in 62 patients undergoing hemodialysis treated nonoperatively or operatively.

MAIN OUTCOME MEASUREMENTS

Clinical outcomes were analyzed to identify factors that may be correlated with life expectancy and functional prognosis.

RESULTS

The overall survival rates in this study at 1-year and 5-years postfracture were found to be 89.8% and 51.5%, respectively. There were significant correlations among the survival rate, patients' age, type of treatment, prefracture ambulation status, and prefracture activities of daily living status. However, using multivariate analysis, the only significant predictor of life expectancy was prefracture ambulation status. As for functional prognosis, the rates of total ambulation recovery and total activities of daily living recovery at 1-year postfracture were 50.0% and 71.2%, respectively. Both patients' age and age at the onset of hemodialysis may contribute considerably to functional prognosis in patients undergoing hemodialysis after femoral neck fracture.

CONCLUSIONS

The present study suggests that the clinical outcomes of patients with femoral neck fractures who undergo hemodialysis are considerably superior to those of previous studies. In addition, when those fractures are treated surgically with specific management in patients undergoing hemodialysis, it may be possible to expect a life expectancy and functional prognosis similar to elderly nonhemodialysis patients with hip fractures.

摘要

目的

确定接受血液透析的患者与老年非血液透析股骨颈骨折患者的预后是否存在差异。

设计

回顾性研究。

地点

一级创伤中心。

患者/干预措施:62例接受血液透析的患者共发生71例股骨颈骨折,进行了非手术或手术治疗。

主要观察指标

分析临床结局,以确定可能与预期寿命和功能预后相关的因素。

结果

本研究中骨折后1年和5年的总生存率分别为89.8%和51.5%。生存率与患者年龄、治疗类型、骨折前行走状态和骨折前日常生活活动状态之间存在显著相关性。然而,通过多变量分析,预期寿命的唯一显著预测因素是骨折前行走状态。至于功能预后,骨折后1年完全恢复行走和完全恢复日常生活活动的比例分别为50.0%和71.2%。患者年龄和开始血液透析的年龄可能对股骨颈骨折后接受血液透析的患者的功能预后有很大影响。

结论

本研究表明,接受血液透析的股骨颈骨折患者的临床结局明显优于以往研究。此外,当对接受血液透析的患者进行手术治疗并采取特定管理措施时,可能预期其预期寿命和功能预后与老年非血液透析髋部骨折患者相似。

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