中华人民共和国法医学检验案件的限制性片段长度多态性分析。

Restriction fragment length polymorphism analysis of forensic science casework in the People's Republic of China.

作者信息

Zhang X W, Lan L, Huo Z Y, Duan B Z, Kobilinsky L

机构信息

Beijing Forensic Science Institute, People's Republic of China.

出版信息

J Forensic Sci. 1991 Mar;36(2):531-6.

PMID:1676722

Abstract

Restriction fragment length polymorphism (RFLP) analysis for the purpose of individualization is now being used in casework in the People's Republic of China. This report describes the use of the multilocus minisatellite probe 33.15 to solve three cases, including two homicides and a rape. In the third case, fetal tissue was analyzed to prove that the alleged rapist was, in fact, the father. In each case, analysis of deoxyribonucleic acid (DNA) resulted in a positive match. The probability of chance association of the DNA fingerprint was calculated as 5.6 x 10(-12), which is similar to the figures reported in the literature.

摘要

为实现个体化目的的限制性片段长度多态性（RFLP）分析目前正在中华人民共和国的实际案件工作中使用。本报告描述了使用多位点小卫星探针33.15解决三个案件的情况，包括两起凶杀案和一起强奸案。在第三个案件中，对胎儿组织进行了分析，以证明被指控的强奸犯实际上是孩子的父亲。在每个案件中，对脱氧核糖核酸（DNA）的分析都得出了阳性匹配结果。DNA指纹偶然匹配的概率计算为5.6×10⁻¹²，这与文献中报道的数字相似。