Lyra Ruy, Oliveira Mônica, Lins Daniel, Cavalcanti Ney
Faculdade de Ciências Médicas de Pernambuco, Universidade de Pernambuco, Recife, PE.
Arq Bras Endocrinol Metabol. 2006 Apr;50(2):239-49. doi: 10.1590/s0004-27302006000200010. Epub 2006 May 23.
Type 2 Diabetes mellitus (DM2) is a complex, multifactorial and worldwide metabolic disease that affects quality and lifestyle of patients. Patients with diabetes can have a 15-year or more reduction of lifetime and the high mortality is due to cardiovascular (CV) complications. Effective strategies for the reduction of the impact of DM2 on CV disorders for the next years and attention concerning to strategies of prevention, mainly for the populations with larger risk of developing the disease, are essential. In that context, impaired glucose tolerance (IGT) and impaired fasting glycemia (IFG) must suffer intervention strategies in order to minimize the risk for diabetes. Behavior modification (diet therapy and physical activity) must be stimulated, and pharmacological agents have to be used when indicated. Studies worldwide have been confirming the effectiveness of lifestyle strategies and even the use of pharmacological agents for the prevention of DM2.
2型糖尿病(DM2)是一种复杂的、多因素的全球性代谢疾病,会影响患者的生活质量和生活方式。糖尿病患者的寿命可能会缩短15年或更长时间,高死亡率归因于心血管(CV)并发症。未来几年,采取有效策略减轻DM2对心血管疾病的影响,并关注预防策略,尤其是针对疾病发生风险较高人群的策略,至关重要。在这种情况下,糖耐量受损(IGT)和空腹血糖受损(IFG)必须接受干预策略,以将糖尿病风险降至最低。必须鼓励行为改变(饮食疗法和体育活动),并在必要时使用药物。世界各地的研究一直在证实生活方式策略甚至使用药物预防DM2的有效性。