Fujioka Sayuri, Karashima Kaoruko, Nakagawa Hidemitsu, Saito Yoshihiro, Nishikawa Norikiyo
Department of Ophthalmology, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka, Japan.
Jpn J Ophthalmol. 2006 May-Jun;50(3):224-8. doi: 10.1007/s10384-005-0312-y.
To investigate and classify the ophthalmic artery (OA) flow patterns in patients with occlusive carotid artery disease (OCAD).
Forty-three patients (52 eyes) with documented OCAD of > or =70% underwent orbital color Doppler imaging. The eyes were first divided into four groups by peak systolic velocity in OA (PSV(OA)): group A, PSV(OA) < or = 0; group B, 0 < PSV(OA) < or = 10; group C, 10 < PSV(OA) < or = 40; and group D, PSV(OA) > 40 cm/s, then further classified by the shape of the OA flow wave. The groups were then compared with respect to the collateral pathway (Co-Path), severity of the OCAD, and systemic diseases.
Eyes with unidirectional reverse flow (group A(1)) had a Co-Path from the ipsilateral external carotid artery and 70%-100% OCAD. Eyes with bidirectional reverse flow (group A(2)) had no Co-Path, 75% OCAD, and impending ischemic heart disease (IHD). Group B eyes had dome-shaped OA flow waves with no Co-Path and 99%-88% OCAD. Group C(1) eyes, with normal flow waves, had a Co-Path from the contralateral internal carotid artery and 100% OCAD. Group C(2) eyes, with triangular-shaped flow waves, had no Co-Path, 93%-70% OCAD, and IHD. Group D eyes had normal high flow waves with no Co-Path, 75% OCAD, and hypertension.
The OA flow patterns were variously affected by collateral pathway, severity of OCAD, and systemic diseases.
研究并分类闭塞性颈动脉疾病（OCAD）患者的眼动脉（OA）血流模式。
43例（52只眼）记录显示OCAD≥70%的患者接受眼眶彩色多普勒成像检查。首先根据OA的收缩期峰值流速（PSV(OA)）将眼睛分为四组：A组，PSV(OA)≤0；B组，0＜PSV(OA)≤10；C组，10＜PSV(OA)≤40；D组，PSV(OA)＞40 cm/s，然后再根据OA血流波形的形状进一步分类。然后比较各组的侧支循环途径（Co-Path）、OCAD的严重程度和全身疾病情况。
单向逆流的眼睛（A(1)组）有来自同侧颈外动脉的侧支循环途径和70%-100%的OCAD。双向逆流的眼睛（A(2)组）没有侧支循环途径、75%的OCAD和即将发生的缺血性心脏病（IHD）。B组眼睛的OA血流波形呈圆顶状，没有侧支循环途径和99%-88%的OCAD。C(1)组眼睛血流波形正常，有来自对侧颈内动脉的侧支循环途径和100%的OCAD。C(2)组眼睛血流波形呈三角形，没有侧支循环途径、93%-70%的OCAD和IHD。D组眼睛有正常的高血流波形，没有侧支循环途径、75%的OCAD和高血压。
OA血流模式受侧支循环途径、OCAD严重程度和全身疾病的不同影响。
