Sacco Simona, Olivieri Luigi, Bastianello Stefano, Carolei Antonio
Department of Neurology, University of L'Aquila, 67100, L'Aquila, Italy.
J Headache Pain. 2006 Sep;7(4):222-30. doi: 10.1007/s10194-006-0300-8. Epub 2006 Jun 15.
The identification of comorbid disorders in migraineurs is important since it may impose therapeutic challenges and limit treatment options. Moreover, the study of comorbidity might lead to improve our knowledge about causes and consequences of migraine. Comorbid neuropathologies in migraine may involve mood disorders (depression, mania, anxiety, panic attacks), epilepsy, essential tremor, stroke, and white matter abnormalities. Particularly, a complex bidirectional relation exists between migraine and stroke, including migraine as a risk factor for cerebral ischemia, migraine caused by cerebral ischemia, migraine as a cause of stroke, migraine mimicking cerebral ischemia, migraine and cerebral ischemia sharing a common cause, and migraine associated with subclinical vascular brain lesions.
偏头痛患者共病障碍的识别很重要，因为这可能带来治疗挑战并限制治疗选择。此外，对共病的研究可能有助于增进我们对偏头痛病因及后果的了解。偏头痛中共病的神经病理学可能涉及情绪障碍（抑郁、躁狂、焦虑、惊恐发作）、癫痫、特发性震颤、中风和白质异常。特别是，偏头痛与中风之间存在复杂的双向关系，包括偏头痛作为脑缺血的危险因素、由脑缺血引起的偏头痛、偏头痛作为中风的病因、偏头痛模拟脑缺血、偏头痛和脑缺血有共同病因，以及偏头痛与亚临床脑血管病变相关。
