Yoshimi Ryusuke, Takeno Mitsuhiro, Yamanaka Shoji, Shiina Masaaki, Kirino Yohei, Takeda Yukiko, Sekiguchi Akiko, Kobayashi Hiroshi, Ihata Atsushi, Motoji Kyosuke, Ohno Shigeru, Ueda Atsuhisa, Soga Takayoshi, Ishigatsubo Yoshiaki
Department of Internal Medicine and Clinical Immunology, Yokohama City University Graduate School of Medicine, 3-9 Fukuura, Kanazawa-ku, Yokohama, 236-0004, Japan.
Mod Rheumatol. 2006;16(3):165-8. doi: 10.1007/s10165-006-0472-8.
A 55-year-old man, diagnosed with systemic sclerosis (SSc) for 20 years, was admitted to our hospital for exertional dyspnea and pleural effusion. Computed tomography scan and cytological findings of the pleural fluid suggested malignant mesothelioma. In the postmortem examination, the tumor was pathologically diagnosed as pseudomesotheliomatous adenocarcinoma (PMA) of the lung, classified into pleomorphic carcinoma with adenocarcinoma component according to the new World Health Organization guidelines. This is the first case report of SSc with PMA.