Newman Karla, Mason Rod S
Department of Chemistry, University of Wales Swansea, Singleton Park, Swansea SA2 8PP, UK.
Rapid Commun Mass Spectrom. 2006;20(14):2067-73. doi: 10.1002/rcm.2560.
Representative organic vapors have been introduced into the flowing afterglow of a low power (<5 W) dc-glow discharge, coupled to a quadrupole mass spectrometer. When a positive bias was applied to the ion sampling orifice, the very surprising result was that molecular mass spectra were obtained with a high sensitivity. When a negative bias was applied to the ion sampling orifice, fragmentation of the analyte was observed with an increase in the extent of ion dissociation as the voltage was increased. The breakdown pattern is compound-specific and would be useful in confirming the identity of an unknown sample. When combined with chromatographic separation, the FFGD-MS technique could be used for chemical speciation studies at the sub-picogram level.
已将代表性有机蒸气引入到与四极质谱仪相连的低功率（<5 W）直流辉光放电的流动余辉中。当对离子采样孔施加正偏压时，得到的非常令人惊讶的结果是，以高灵敏度获得了分子质谱。当对离子采样孔施加负偏压时，观察到分析物的碎片化，且随着电压升高离子解离程度增加。击穿模式具有化合物特异性，可用于确认未知样品的身份。当与色谱分离相结合时，FFGD-MS技术可用于亚皮克级的化学形态研究。
