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中重度肺动脉高压患者的手术干预。

Surgical intervention in patients with moderate to severe pulmonary arterial hypertension.

作者信息

Minai Omar A, Venkateshiah Saiprakash B, Arroliga Alejandro C

机构信息

Department of Pulmonary anc Critical Care Medicine, Cleveland Clinic Foundation, OH 44195, USA.

出版信息

Conn Med. 2006 Apr;70(4):239-43.

PMID:16768070
Abstract

BACKGROUND

Patients with pulmonary arterial hypertension are believed to experience severe postoperative complications after major surgery.

METHODS

We retrospectively analyzed the data of 21 patients with pulmonary arterial hypertension who underwent 28 surgical procedures at our institution between 1996 and 2002.

RESULTS

The average mean pulmonary arterial pressure was 53 +/- 14.4 mm Hg. Twenty-two procedures were performed under general anesthesia. Extubation occurred within 24 hours of surgery in 72% and an intensive care unit stay was not required after 43% of the procedures. Perioperative morbidity and mortality were typically related to the surgical procedure or underlying disease.

CONCLUSIONS

In our study, patients with moderate to severe pulmonary arterial hypertension had an 18% per procedure mortality and a 19% rate of right heart failure after surgical intervention.

摘要

背景

肺动脉高压患者被认为在大手术后会出现严重的术后并发症。

方法

我们回顾性分析了1996年至2002年间在我们机构接受28次手术的21例肺动脉高压患者的数据。

结果

平均肺动脉压为53±14.4毫米汞柱。22例手术在全身麻醉下进行。72%的患者在术后24小时内拔管,43%的手术无需入住重症监护病房。围手术期发病率和死亡率通常与手术操作或基础疾病有关。

结论

在我们的研究中,中重度肺动脉高压患者手术干预后每次手术的死亡率为18%,右心衰竭发生率为19%。

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