Inui Tadashi, Shimura Tsuyoshi, Yamamoto Takashi
Department of Behavioral Physiology, Graduate School of Human Sciences, Osaka University, Osaka, Japan.
Behav Neurosci. 2006 Jun;120(3):590-9. doi: 10.1037/0735-7044.120.3.590.
Rats failed to acquire aversions to odor stimulus, which was followed 30 min later by an unconditioned stimulus (US). However, when the odor stimulus was accompanied by a taste stimulus, they acquired odor aversions as well as taste aversions. In this phenomenon, referred to as a taste-potentiated odor aversion, lesions of the amygdala disrupted both taste and odor aversions, whereas lesions of the parvicellular part of ventroposteromedial thalamic nucleus (VPMpc) or insular cortex (IC) disrupted taste aversion but attenuated only odor aversion. These results suggest that both taste and odor stimuli are associated with US in the amygdala and that taste inputs delivered to the amygdala through the IC and/or VPMpc play an important role in potentiation of odor aversion.
大鼠无法对气味刺激形成厌恶，30分钟后会接着出现非条件刺激（US）。然而，当气味刺激伴有味觉刺激时，它们既会形成气味厌恶，也会形成味觉厌恶。在这种被称为味觉增强气味厌恶的现象中，杏仁核损伤会破坏味觉和气味厌恶，而腹后内侧丘脑核小细胞部（VPMpc）或岛叶皮质（IC）损伤会破坏味觉厌恶，但只会减弱气味厌恶。这些结果表明，味觉和气味刺激在杏仁核中均与非条件刺激相关联，并且通过IC和/或VPMpc传递至杏仁核的味觉输入在增强气味厌恶方面发挥着重要作用。
