Dahl Jørgen B, Kehlet Henrik
Amtssygehuset i Glostrup, Operations- og Anaestesiologisk Afdeling, og H:S Rigshospitalet, Juliane Marie Centret, Sektion for Kirurgisk Patofysiologi.
Ugeskr Laeger. 2006 May 15;168(20):1986-8.
Substantial progress has been made in our understanding of acute pain mechanisms, and our insight into postoperative convalescence and rehabilitation has increased dramatically. There is a lack of evidence for pre-emptive analgesia, whereas studies of antihyperalgesic drugs and multimodal analgesic regimens are promising. The use of opioids should be restricted, and it may be rational to develop procedure-specific pain treatment guidelines. There is a need for increased collaboration and integration of acute pain treatment and multimodal postoperative rehabilitation efforts.
我们对急性疼痛机制的理解取得了重大进展，并且我们对术后康复的认识也有了显著提高。目前缺乏关于超前镇痛的证据，而对抗痛觉过敏药物和多模式镇痛方案的研究很有前景。阿片类药物的使用应受到限制，制定针对具体手术的疼痛治疗指南可能是合理的。需要加强急性疼痛治疗与多模式术后康复工作的协作与整合。
