Anderson David E, Muir William W
Department of Veterinary Clinical Sciences, College of Veterinary Medicine, The Ohio State University, 601 Tharp Street, Columbus, OH 43210, USA.
Vet Clin North Am Food Anim Pract. 2005 Mar;21(1):19-31. doi: 10.1016/j.cvfa.2004.12.008.
Based on the available literature, the most important tool available in modern veterinary medicine is preemptive analgesia. Veterinarians must capture "opportunities" to prevent the onset of pain, prevent noxious stimuli or their perception, and limit the pain-stress-distress cascade that results in altered behavior and deviation from physiologic norms. Rational treatment of pain requires an appreciation of its consequences, a fundamental understanding of the mechanisms that are responsible for its production,and a practical appreciation of the analgesic drugs that are available. The goal of pain treatment should be to restore normal (physiologic) pain responses and to eliminate pathologic pain processes. In this context, pain therapy should be directed at the multiple mechanisms (multimodal therapy)responsible for its production, and analgesic therapies should be instituted before (preemptive therapy) pain is initiated (eg, surgery) whenever possible.
根据现有文献,现代兽医学中最重要的工具是超前镇痛。兽医必须抓住“机会”来预防疼痛的发作,防止有害刺激或对其的感知,并限制导致行为改变和偏离生理规范的疼痛-应激-痛苦级联反应。合理的疼痛治疗需要认识到其后果,对产生疼痛的机制有基本的了解,以及对现有镇痛药有实际的认识。疼痛治疗的目标应该是恢复正常(生理)疼痛反应并消除病理性疼痛过程。在这种情况下,疼痛治疗应针对产生疼痛的多种机制(多模式治疗),并且只要有可能,应在疼痛开始(例如手术)之前(超前治疗)就开始镇痛治疗。