Innis Sheila M, Palaty Jan, Vaghri Ziba, Lockitch Gillian
Nutrition Research Program, Department of Paediatrics, University of British Columbia, Vancouver, British Columbia, Canada.
J Pediatr. 2006 Jun;148(6):759-63. doi: 10.1016/j.jpeds.2006.02.001.
To assess exposure to mercury (Hg) among children in population subgroups whose traditional dietary practices include fish.
We determined blood Hg, red blood cell phosphatidylethanolamine omega-3 eicosapentaenoic acid as a marker of fish intake, and assessed indexes of childhood behavior in preschool children 1.5 to 5 years of age (n = 228) living in an ethnically diverse neighborhood in Vancouver, British Columbia, Canada.
The median blood Hg was 4.6 nmol/L, range 0-67.9 nmol/L. Twelve (6%) children, all of whom were Chinese, had a blood Hg > 28.9 nmol/L. Blood Hg, total fish intake, and eicosapentaenoic acid were higher among Chinese than Caucasian children; however, higher fish intake did not predict blood Hg. Blood Hg was inversely associated with attentional focusing in children over 3 years of age after adjusting for confounding family variables, iron deficiency anemia, and zinc deficiency. Major sources of fish among Chinese children were imported fish rather than local fish.
Children from population subgroups within populations not considered at risk may be at increased risk of neurotoxicity caused by Hg exposure from fish.
评估传统饮食习惯中包含鱼类的人群亚组中儿童的汞（Hg）暴露情况。
我们测定了血汞、红细胞磷脂酰乙醇胺ω-3二十碳五烯酸作为鱼类摄入量的标志物，并评估了居住在加拿大不列颠哥伦比亚省温哥华一个种族多样化社区的1.5至5岁学龄前儿童（n = 228）的儿童行为指标。
血汞中位数为4.6 nmol/L，范围为0 - 67.9 nmol/L。12名（6%）儿童血汞> 28.9 nmol/L，他们均为华裔。华裔儿童的血汞、鱼类总摄入量和二十碳五烯酸水平高于白人儿童；然而，鱼类摄入量较高并不能预测血汞水平。在调整了混杂的家庭变量、缺铁性贫血和锌缺乏后，血汞与3岁以上儿童的注意力集中呈负相关。华裔儿童的鱼类主要来源是进口鱼而非本地鱼。
来自未被视为有风险人群中的人群亚组的儿童，可能因鱼类汞暴露而面临神经毒性风险增加。
