Byrne Thomas N, Borges Lawrence F, Loeffler Jay S
Department of Neurology and Health Sciences Technology, Harvard Medical School and Massachusetts General Hospital, Boston, 02114, USA.
Semin Oncol. 2006 Jun;33(3):307-11. doi: 10.1053/j.seminoncol.2006.03.002.
Until recently, patients with metastatic epidural spinal cord compression (MESCC) were routinely treated with corticosteroids and radiotherapy (RT). However, major advances in imaging, recognition of new prognostic factors, and new techniques in RT and surgery have led to a number of management choices that need to be considered when treating a patient with MESCC. In our view, the management should be individualized taking into account many variables. We present here some of the advances we believe are among the most important. A historical background to the modern management of this condition is first presented.
直到最近,转移性硬膜外脊髓压迫症(MESCC)患者仍常规接受皮质类固醇和放射治疗(RT)。然而,影像学的重大进展、新预后因素的识别以及放疗和手术新技术的出现,导致了在治疗MESCC患者时需要考虑多种管理选择。我们认为,管理应考虑诸多变量进行个体化。在此,我们介绍一些我们认为最重要的进展。首先介绍这种疾病现代管理的历史背景。