Watson R Scott, O'Rourke P Pearl, Bartlett Robert H
The CRISMA Laboratory (Clinical Research, Investigation, and Systems Modeling of Acute Illness), and Division of Pediatric Critical Care Medicine, Department of Critical Care Medicine, University of Pittsburgh, Pittsburgh, PA 15261, USA.
J Crit Care. 2006 Jun;21(2):151-5. doi: 10.1016/j.jcrc.2006.03.001.
In this Classic Papers feature, we highlight Dr. Robert H. Bartlett's ground-breaking case series from 1977 reporting 28 pediatric and adult patients supported by extracorporeal membrane oxygenation (ECMO). Dr. P. Peal O'Rourke, who conducted early, innovative clinical research on ECMO, provides her perspective on the state of critical care for children in the late 1970s, how this paper and Dr. Bartlett himself influenced it, and difficulties faced in developing ECMO programs in the 1980s. Dr. Bartlett offers answers to questions about how his work on ECMO began, the reaction of the critical care community to the use of ECMO, and how challenges in studying ECMO in clinical trials have been approached.
在本期经典论文专题中,我们重点介绍罗伯特·H·巴特利特博士1977年具有开创性的病例系列,该系列报告了28例接受体外膜肺氧合(ECMO)支持的儿科和成人患者。对ECMO进行早期创新临床研究的P. 皮尔·奥罗克博士阐述了她对20世纪70年代末儿童重症监护状况的看法,以及这篇论文和巴特利特博士本人对其产生的影响,还有20世纪80年代在开展ECMO项目时所面临的困难。巴特利特博士回答了关于他的ECMO研究工作如何起步、重症监护界对ECMO使用的反应,以及在临床试验中研究ECMO所面临的挑战是如何应对的等问题。