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地松鼠(Citellus citellus)出生后发育过程中,单胺氧化酶活性的发展。

Development of monoamine oxidase activity during postnatal development of the ground squirrel (Citellus citellus).

作者信息

Petrović V M, Janić-Sibalić V, Cvijić G

机构信息

Institute of Physiology and Biochemistry, Faculty of Science, University of Belgrade, Yugoslavia.

出版信息

Comp Biochem Physiol C Comp Pharmacol Toxicol. 1991;98(2-3):377-80.

PMID:1676952
Abstract
  1. Monoamine oxidase (MAO) activity in the brain and peripheral tissues of newborn ground squirrel, as well as its evolution during postnatal development were studied. 2. Monoamine oxidase activity in the brain stem and liver, at the day of birth is significantly higher (P less than 0.01; P less than 0.005) than in adults. 3. After that, enzyme activity decreases, but at the 25th day, e.g. at the day of the opening of the eyes, still remains significantly above the adult's value (P less than 0.01). 4. The results indicate some species specificity concerning the level and the evolution of cerebral and hepatic MAO activity as compared to the rats.
摘要
  1. 研究了新生地松鼠脑和外周组织中的单胺氧化酶(MAO)活性及其在出生后发育过程中的变化。2. 出生当天,脑干和肝脏中的单胺氧化酶活性显著高于成年动物(P<0.01;P<0.005)。3. 此后,酶活性下降,但在第25天,例如睁眼当天,仍显著高于成年动物的值(P<0.01)。4. 结果表明,与大鼠相比,脑和肝脏MAO活性的水平及变化存在一定的物种特异性。

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