Levanon Erez Y, Eisenberg Eli
School of Physics and Astronomy, Raymond and Beverly Sackler Faculty of Exact Sciences, Tel Aviv University, Tel Aviv 69978, Israel.
Brief Funct Genomic Proteomic. 2006 Mar;5(1):43-5. doi: 10.1093/bfgp/ell014. Epub 2006 Feb 22.
Recently a number of groups have introduced computational methods for the detection of A-to-I RNA editing sites. These approaches have resulted in finding thousands of editing sites within the genomic repeats, as well as a few novel genetic recoding sites. We review these recent advancements, emphasizing the principles underlying the various methods used. Possible directions for extending these methods are discussed.
最近,一些研究团队引入了用于检测A到I RNA编辑位点的计算方法。这些方法已在基因组重复序列中发现了数千个编辑位点,以及一些新的遗传重编码位点。我们回顾这些最新进展,重点介绍所用各种方法的基本原理。并讨论了扩展这些方法的可能方向。