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心脏导管插入术后的缺血性中风:合适的溶栓候选者?

Ischemic strokes after cardiac catheterization: opportune thrombolysis candidates?

作者信息

Khatri Pooja, Kasner Scott E

机构信息

Department of Neurology, University of Cincinnati, Cincinnati, Ohio, USA.

出版信息

Arch Neurol. 2006 Jun;63(6):817-21. doi: 10.1001/archneur.63.6.817.

DOI:10.1001/archneur.63.6.817
PMID:16769862
Abstract

Stroke is an important complication after cardiac catheterization procedures, resulting in death and disability for thousands of patients each year. Common risk factors include advanced age, vascular comorbidities, and more complicated and invasive procedures. Several lines of evidence suggest that these strokes are embolic, from either dislodgement of a clot or atheromatous debris off the aortic arch or from thrombus formation on the tip of a guide catheter. These strokes are likely amenable to thrombolysis, although the current literature regarding the use of thrombolysis in this setting is limited to case reports and series. Whether thrombolysis is safe and efficacious remains to be determined, but the existing evidence seems favorable for individual circumstances.

摘要

中风是心脏导管插入术后的一种重要并发症,每年导致数千名患者死亡和残疾。常见的风险因素包括高龄、血管合并症以及更复杂和侵入性更强的手术。有几条证据表明,这些中风是栓塞性的,要么是主动脉弓上的凝块或动脉粥样硬化碎片脱落,要么是导引导管尖端形成血栓。这些中风可能适合溶栓治疗,尽管目前关于在这种情况下使用溶栓治疗的文献仅限于病例报告和系列研究。溶栓治疗是否安全有效仍有待确定,但现有证据在个别情况下似乎是有利的。

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