Shirakawa Takashi, Tanaka Noritake, Yokoi Kimiyoshi, Ishikawa Noriyuki, Seya Tomoko, Horiba Kouji, Yamada Takeshi, Kanazawa Yoshikazu, Okawa Keiichi, Yoshioka Masato, Oaki Yoshiharu, Tokunaga Akira, Tajiri Takashi
Dept. of Surgery, Nippon Medical School Chiba Hokuso Hospital.
Gan To Kagaku Ryoho. 2006 Jun;33(6):811-5.
A 65-year-old female with unresectable advanced gastric cancer accompanied by multiple lung metastases underwent jejunostomy and was treated with TS-1 and CDDP. One course consisted of TS-1 (80 mg/day) via an intestinal fistula tube from days 1 to 14 followed by 14 days rest and CDDP (80 mg/day) was administered by 24-hour continuous intravenous infusion on day 8. After 3 courses, the primary tumor and lymph node metastases decreased in size (PR), and CT scan showed the multiple lung metastases had disappeared. Total gastrectomy (D 2) and splenectomy were performed after chemotherapy. The final diagnosis was Stage IIIA and the pathological response to chemotherapy was Grade 2. The patient has survived for over 14 months after surgery and has presented no signs of recurrence.
