Schober R, Nelson D
Arch Pathol. 1975 Aug;99(8):403-10.
A pituitary adenoma with amyloid deposits was studied by light and electron microscopy. The amyloid material was radially oriented, deposited in the extracellular space, and often intermingled with small vesicles. It was surrounded by histiocytes with deep cytoplasmic invaginations. The histiocytes contained large autophagic vacuoles in which amyloid was also present. These features are similar to other forms of amyloidosis and suggest a histiocytic origin of the amyloid.
对一例伴有淀粉样沉积物的垂体腺瘤进行了光镜和电镜研究。淀粉样物质呈放射状排列，沉积于细胞外间隙，常与小泡混合。它被具有深陷胞质内陷的组织细胞所包围。这些组织细胞含有大的自噬泡，其中也存在淀粉样物质。这些特征与其他形式的淀粉样变性相似，提示淀粉样物质起源于组织细胞。
