Hoon Dave S B, Kitago Minoru, Kim Joseph, Mori Takuji, Piris Adriano, Szyfelbein Katherine, Mihm Martin C, Nathanson S David, Padera Timothy P, Chambers Ann F, Vantyghem Sharon A, MacDonald Ian C, Shivers Steven C, Alsarraj Marwan, Reintgen Douglas S, Passlick Bernward, Sienel Wulf, Pantel Klaus
Department of Molecular Oncology, John Wayne Cancer Institute, Santa Monica, CA 90404, USA.
Cancer Metastasis Rev. 2006 Jun;25(2):203-20. doi: 10.1007/s10555-006-8500-x.
A major topic covered at the First International Symposium on Cancer Metastasis and the Lymphovascular System was the molecular mechanisms of metastasis. This has become of major interest in recent years as we have discovered new metastasis-related genes and gained understanding of the molecular events of lymphatic metastasis. The symposium covered new aspects and important questions related to the events of metastasis in both humans and animals. The basic and clinical related research covered in this topic represented many disciplines. The presentations showed novel findings and at the same time, raised many new unanswered questions, indicating the limited knowledge we still have regarding the molecular events of metastasis. The hope is that further unraveling of the direct and indirect molecular events of lymphatic metastasis will lead to new approaches in developing effective therapeutics.
第一届癌症转移与淋巴血管系统国际研讨会涵盖的一个主要主题是转移的分子机制。近年来,这已成为人们主要关注的问题,因为我们发现了新的转移相关基因,并对淋巴转移的分子事件有了更深入的了解。该研讨会涵盖了与人类和动物转移事件相关的新方面和重要问题。本主题涵盖的基础研究和临床相关研究涉及多个学科。这些报告展示了新的发现,同时也提出了许多新的未解决的问题,这表明我们对转移分子事件的了解仍然有限。希望进一步揭示淋巴转移的直接和间接分子事件将为开发有效的治疗方法带来新途径。