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门静脉高压患者结肠手术后慢性造口静脉曲张出血:β受体阻滞剂的疗效?

Chronic stomal variceal bleeding after colonic surgery in patients with portal hypertension: efficacy of beta-blocking agents?

作者信息

Noubibou Myrène, Douala Hortense C, Druez Patrick M, Kartheuser Alex H, Detry Roger J, Geubel André P

机构信息

Departments of Gastroenterology and Abdominal Surgery, St Luc University Hospital, Université Catholique de Louvain, 1200 Bruxelles, Belgium.

出版信息

Eur J Gastroenterol Hepatol. 2006 Jul;18(7):807-8. doi: 10.1097/01.meg.0000224480.74298.0a.

DOI:10.1097/01.meg.0000224480.74298.0a
PMID:16772844
Abstract

In patients with portal hypertension, ileostomy or colostomy carries the risk of the development of stomal varices at the site of the mucocutaneous junction of a stoma. Such varices are often the source of difficult-to-treat recurrent or chronic bleeding. In this setting, transjugular intrahepatic portosystemic shunt insertion and embolisation is considered the best therapeutic approach in spite of relatively high mortality and morbidity rates. We report the cases of three consecutive patients with portal hypertension of various causes and chronic stomal variceal bleeding in whom beta-blocking therapy resulted in the drying up of bleeding and the prevention of its recurrence for periods of time ranging between 2 and 42 months.

摘要

在门静脉高压患者中,回肠造口术或结肠造口术有在造口黏膜皮肤交界处发生造口静脉曲张的风险。此类静脉曲张常常是难以治疗的复发性或慢性出血的来源。在这种情况下,尽管经颈静脉肝内门体分流术(TIPS)置入和栓塞的死亡率和发病率相对较高,但仍被认为是最佳治疗方法。我们报告了3例连续的门静脉高压患者,病因各异,均有慢性造口静脉曲张出血,β受体阻滞剂治疗使出血停止,并在2至42个月的时间段内预防了出血复发。

相似文献

1
Chronic stomal variceal bleeding after colonic surgery in patients with portal hypertension: efficacy of beta-blocking agents?门静脉高压患者结肠手术后慢性造口静脉曲张出血:β受体阻滞剂的疗效?
Eur J Gastroenterol Hepatol. 2006 Jul;18(7):807-8. doi: 10.1097/01.meg.0000224480.74298.0a.
2
[Recurrent stomal hemorrhage treated by transjugular intrahepatic portosystemic anastomosis and embolization of stomal varices].经颈静脉肝内门体分流术及吻合口静脉曲张栓塞术治疗复发性吻合口出血
J Radiol. 1998 Jul;79(7):690-2.
3
Stomal varices: a rare cause of stomal hemorrhage. A report of three cases.造口静脉曲张:造口出血的罕见原因。三例报告。
Ostomy Wound Manage. 2007 Aug;53(8):20-2, 24, 26 passim.
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Transjugular intrahepatic portosystemic shunt for bleeding stomal varices associated with chronic portal vein occlusion: long-term angiographic, hemodynamic, and clinical follow-up.经颈静脉肝内门体分流术治疗与慢性门静脉闭塞相关的出血性吻合口静脉曲张:长期血管造影、血流动力学及临床随访
Am J Gastroenterol. 2000 Oct;95(10):2966-8. doi: 10.1111/j.1572-0241.2000.03211.x.
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Stomal varices: management with decompression tips and transvenous obliteration or sclerosis.造口静脉曲张:采用减压尖端及经静脉闭塞或硬化治疗
Tech Vasc Interv Radiol. 2013 Jun;16(2):176-84. doi: 10.1053/j.tvir.2013.02.005.
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Bleeding stomal varices: case series and systematic review of the literature.出血性吻合口静脉曲张:病例系列及文献系统综述
Clin Gastroenterol Hepatol. 2008 Mar;6(3):346-52. doi: 10.1016/j.cgh.2007.12.047.
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Treatment of stomal variceal hemorrhage with TIPS: case report and review of the literature.经颈静脉肝内门体分流术治疗造口静脉曲张出血:病例报告及文献综述
Cardiovasc Intervent Radiol. 2000 Jul-Aug;23(4):301-3. doi: 10.1007/s002700010073.
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[Variceal hemorrhage on the colostomy area in a patient with portal hypertension].
Rev Esp Enferm Dig. 1991 Jun;79(6):437-8.
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[Hemorrhage due to peristomal ectopic varices: an infrequent complication of portal hypertension].[造口周围异位静脉曲张出血:门静脉高压症的罕见并发症]
Gastroenterol Hepatol. 2006 May;29(5):320-1. doi: 10.1157/13087474.
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Reduction in portal venous pressure by transjugular intrahepatic portosystemic shunt for treatment of hemorrhagic stomal varices.经颈静脉肝内门体分流术降低门静脉压力治疗出血性贲门周围静脉曲张。
AJR Am J Roentgenol. 2014 Sep;203(3):668-73. doi: 10.2214/AJR.13.12211.

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Role of a Stoma Nurse in the Management of the Specific Stoma-Related Complications.造口护士在特定造口相关并发症管理中的作用。
Curr Health Sci J. 2024 Jan-Mar;50(1):5-11. doi: 10.12865/CHSJ.50.01.01. Epub 2024 Mar 31.
2
Use of Non-Selective Beta-Blocker for Refractory Stomal Variceal Hemorrhage.使用非选择性β受体阻滞剂治疗难治性造口静脉曲张出血。
Case Rep Gastroenterol. 2021 Jan 26;15(1):87-91. doi: 10.1159/000510921. eCollection 2021 Jan-Apr.
3
Ostomy-Related Complications.造口相关并发症
Clin Colon Rectal Surg. 2019 May;32(3):176-182. doi: 10.1055/s-0038-1676995. Epub 2019 Apr 2.
4
Hemorrhagic ascites from spontaneous ectopic mesenteric varices rupture in NASH induced cirrhosis and successful outcome: a case report.非酒精性脂肪性肝炎(NASH)所致肝硬化中自发性异位肠系膜静脉曲张破裂引起的出血性腹水及成功治疗病例报告
World J Gastroenterol. 2014 Jul 7;20(25):8292-7. doi: 10.3748/wjg.v20.i25.8292.
5
Management of parastomal varices: who re-bleeds and who does not? A systematic review of the literature.肠造口旁静脉曲张的处理:再出血者和未再出血者的特征?文献系统评价。
Tech Coloproctol. 2013 Apr;17(2):163-70. doi: 10.1007/s10151-012-0922-6. Epub 2012 Nov 14.
6
Updates in the pathogenesis, diagnosis and management of ectopic varices.异位静脉曲张的发病机制、诊断和治疗的新进展。
Hepatol Int. 2008 Sep;2(3):322-34. doi: 10.1007/s12072-008-9074-1. Epub 2008 May 31.