Jackowski Christian, Thali Michael J, Buck Ursula, Aghayev Emin, Sonnenschein Martin, Yen Kathrin, Dirnhofer Richard, Vock Peter
Institute of Forensic Medicine, Interventional and Pediatric Radiology, Inselspital, University of Bern, Switzerland.
Invest Radiol. 2006 Jul;41(7):572-8. doi: 10.1097/01.rli.0000221323.38443.8d.
Computed tomography (CT) and magnetic resonance imaging (MRI) are introduced as an alternative to traditional autopsy. The purpose of this study was to investigate their accuracy in mass estimation of liver and spleen.
In 44 cases, the weights of spleen and liver were estimated based on MRI and CT data using a volume-analysis software and a postmortem tissue-specific density factor. In a blinded approach, the results were compared with the weights noted at autopsy.
Excellent correlation between estimated and real weights (r = 0.997 for MRI, r = 0.997 for CT) was found. Putrefaction gas and venous air embolism led to an overestimation. Venous congestion and drowning caused higher estimated weights.
Postmortem weights of liver and spleen can accurately be assessed by nondestructive imaging. Multislice CT overcomes the limitation of putrefaction and venous air embolism by the possibility to exclude gas. Congestion seems to be even better assessed.
计算机断层扫描（CT）和磁共振成像（MRI）被引入作为传统尸检的替代方法。本研究的目的是调查它们在肝脏和脾脏质量估计中的准确性。
在44例病例中，使用体积分析软件和死后组织特异性密度因子，根据MRI和CT数据估计脾脏和肝脏的重量。采用盲法将结果与尸检时记录的重量进行比较。
发现估计重量与实际重量之间具有极好的相关性（MRI的r = 0.997，CT的r = 0.997）。腐败气体和静脉空气栓塞导致高估。静脉淤血和溺水导致估计重量更高。
肝脏和脾脏的死后重量可以通过无损成像准确评估。多层CT通过排除气体的可能性克服了腐败和静脉空气栓塞的限制。淤血似乎可以得到更好的评估。
