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夜间角膜塑形术对特定屈光不正生活质量的影响。

The effect of overnight contact lens corneal reshaping on refractive error-specific quality of life.

作者信息

Berntsen David A, Mitchell G Lynn, Barr Joseph T

机构信息

The Ohio State University College of Optometry, Columbus, Ohio 43210, USA.

出版信息

Optom Vis Sci. 2006 Jun;83(6):354-9. doi: 10.1097/01.opx.0000221401.33776.54.

Abstract

PURPOSE

The purpose of this study is to determine the effect of corneal refractive therapy (CRT) on refractive error-specific quality of life.

METHODS

The National Eye Institute Refractive Error Quality of Life Instrument (NEI RQL-42) was administered to 20 myopic patients (mean spherical equivalent -3.11 D +/- 0.96 D) between the ages of 21 and 37 years both before and 1 month after being successfully fit with Paragon CRT lenses. High- and low-contrast best-corrected visual acuity (BCVA) and higher-order aberrations were also measured. Scores for the 13 NEI RQL-42 subscales were calculated and a Wilcoxon sign rank test was used to determine whether there was a significant change in each of the subscale scores. Post hoc power analyses were also performed.

RESULTS

Statistically significant changes were found in three of the 13 NEI RQL-42 subscales. Significant improvements in subscale score were found for the symptoms (mean +/- standard deviation, 10.18 +/- 10.57, p = 0.0007) and dependence on correction (43.13 +/- 27.42, p < 0.0001) subscales. A significant reduction was found in the glare subscale (-32.50 +/- 35.22, p = 0.001). No significant changes were found in the clarity of vision, expectations, near vision, far vision, diurnal fluctuations, activity limitations, worry, suboptimal correction, appearance, or satisfaction with correction subscales.

CONCLUSIONS

CRT may improve a patient's perception of their visual independence, decrease the amount of ocular symptoms they report, and increase symptoms of glare. A larger, well-controlled clinical trial is necessary to verify these results. An increase in patient-reported glare is likely the result of measured increases in higher-order aberrations after CRT, especially spherical aberration under mesopic and scotopic conditions.

摘要

目的

本研究旨在确定角膜塑形术(CRT)对特定屈光不正生活质量的影响。

方法

对20名年龄在21至37岁之间的近视患者(平均等效球镜度数为-3.11 D±0.96 D)在成功佩戴Paragon CRT镜片之前和之后1个月进行了美国国立眼科研究所屈光不正生活质量量表(NEI RQL-42)评估。还测量了高对比度和低对比度最佳矫正视力(BCVA)以及高阶像差。计算了NEI RQL-42的13个分量表的得分,并使用Wilcoxon符号秩检验来确定每个分量表得分是否有显著变化。还进行了事后功效分析。

结果

在NEI RQL-42的13个分量表中,有3个发现了统计学上的显著变化。症状分量表(平均±标准差,10.18±10.57,p = 0.0007)和对矫正的依赖分量表(43.13±27.42,p < 0.0001)的得分有显著改善。眩光分量表有显著降低(-32.50±35.22,p = 0.001)。在视力清晰度、期望、近视力、远视力、昼夜波动、活动限制、担忧、矫正不足、外观或对矫正的满意度分量表中未发现显著变化。

结论

CRT可能会改善患者对视觉独立性的感知,减少他们报告的眼部症状数量,并增加眩光症状。需要进行更大规模、严格控制的临床试验来验证这些结果。患者报告的眩光增加可能是CRT后测量到的高阶像差增加的结果,尤其是在中间视觉和暗视觉条件下的球差。

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