Katdare M V, Fichera A, Heimann T M
Department of Surgery, University of Chicago, USA.
Tech Coloproctol. 2006 Jul;10(2):143-6. doi: 10.1007/s10151-006-0269-y. Epub 2006 Jun 19.
Two brothers with familial carcinoid tumors of the rectum are presented. A few cases documenting the occurrence of carcinoid tumors in first-degree relatives in the absence of the multiple endocrine neoplasia (MEN) syndromes have been reported in the literature. Consistent with these previous reports, in this case both patients had gastrointestinal carcinoid tumors that are located in identical anatomic locations. The current literature on carcinoid tumors outside the setting of any known genetic syndrome is reviewed. Clinical relevance and screening recommendations are discussed.
本文介绍了两例患有家族性直肠类癌肿瘤的兄弟。文献中已报道了一些病例，记录了在无多发性内分泌肿瘤（MEN）综合征的情况下，一级亲属中发生类癌肿瘤的情况。与这些先前的报道一致，在本病例中，两名患者均患有位于相同解剖位置的胃肠道类癌肿瘤。本文综述了关于任何已知遗传综合征背景之外的类癌肿瘤的现有文献。并讨论了临床相关性和筛查建议。
