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使用血管内支架移植物对胸降主动脉急性破裂进行紧急治疗。

Emergency treatment of acute rupture of the descending thoracic aorta using endovascular stent-grafts.

作者信息

Amabile Philippe, Rollet Gilles, Vidal Vincent, Collart Frédéric, Bartoli Jean-Michel, Piquet Philippe

机构信息

Service de Chirurgie Vasculaire, Hôpital Sainte Marguerite, Marseille, France.

出版信息

Ann Vasc Surg. 2006 Nov;20(6):723-30. doi: 10.1007/s10016-006-9096-x.

DOI:10.1007/s10016-006-9096-x
PMID:16773489
Abstract

Open surgical management of acute rupture of the descending thoracic aorta (DTA) is associated with high mortality and morbidity. Endovascular stent-grafts (ESGs) could provide a less invasive treatment alternative to conventional open surgery. The purpose of this report detailing our experience using ESG for treatment of acute rupture of the DTA is to determine the indications for endovascular repair. From June 2000 to April 2005, 17 patients presenting rupture of the DTA were treated using commercially available ESGs at our institution. There were two women and 15 men, with a mean age of 41.9 +/- 20.5 years. The cause of aortic rupture was traumatic in 13 cases and nontraumatic in four. Treatment was undertaken immediately in 10 cases and delayed in seven (range 5-68 days, mean 23.5). In one patient, the proximal neck landing zone was prepared prior to endovascular repair. No patients died during the postoperative period. The technical success rate was 84%. One patient developed a proximal type 1 endoleak at the end of the procedure. Three complications, i.e., two iliac dissections and one femoral artery rupture, occurred during the procedure. No paraplegia was observed. Mean follow-up was 13.3 months (range 1-41). One patient treated for traumatic rupture was lost from follow-up 21 months after initial treatment. No procedure-related complication was observed in this traumatic rupture group. Control computed tomographic scan at 13 months following the procedure demonstrated no evidence of periprosthetic leak or false aneurysm. In the nontraumatic rupture group, two patients died of aortic rupture and one treated for aortobronchial fistula developed recurrent hemoptysis 23 months after initial treatment and required placement of two additional ESGs. The immediate outcome of covered stent-graft placement for management of acute aortic rupture of the DTA is good. However, long-term surveillance is mandatory, especially in patients treated for nontraumatic aortic rupture that is associated with a high late complication rate. Further study will be needed to determine the exact utility of endovascular therapy for aortic rupture: final treatment or bridge to conventional open-chest repair when the patient's condition has stabilized.

摘要

胸降主动脉(DTA)急性破裂的开放手术治疗死亡率和发病率都很高。血管内支架移植物(ESG)可为传统开放手术提供侵入性较小的治疗选择。本报告详细介绍了我们使用ESG治疗DTA急性破裂的经验,目的是确定血管内修复的适应证。2000年6月至2005年4月,我院使用市售ESG治疗了17例DTA破裂患者。其中女性2例,男性15例,平均年龄41.9±20.5岁。主动脉破裂的原因,外伤13例,非外伤4例。10例立即进行治疗,7例延迟治疗(5 - 68天,平均23.5天)。1例患者在血管内修复前准备了近端颈部着陆区。术后无患者死亡。技术成功率为84%。1例患者在手术结束时出现近端I型内漏。术中发生3例并发症,即2例髂动脉夹层和1例股动脉破裂。未观察到截瘫。平均随访13.3个月(1 - 41个月)。1例因外伤破裂接受治疗的患者在初始治疗后21个月失访。该外伤破裂组未观察到与手术相关的并发症。术后13个月的对照计算机断层扫描显示,没有人工血管周围渗漏或假性动脉瘤的证据。在非外伤破裂组中,2例患者死于主动脉破裂,1例因主支气管瘘接受治疗的患者在初始治疗后23个月出现反复咯血,需要额外放置2个ESG。采用带覆膜支架移植物治疗DTA急性主动脉破裂的近期效果良好。然而,必须进行长期监测,尤其是对于非外伤主动脉破裂患者,其晚期并发症发生率较高。需要进一步研究以确定血管内治疗对主动脉破裂的确切效用:是最终治疗方法还是在患者病情稳定后作为传统开胸修复的桥梁。

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