Amabile Philippe, Collart Frédéric, Gariboldi Vlad, Rollet Gilles, Bartoli Jean-Michel, Piquet Philippe
Department of Vascular Surgery, Hôpital Sainte Marguerite, 13009 Marseille, France.
J Vasc Surg. 2004 Nov;40(5):873-9. doi: 10.1016/j.jvs.2004.08.053.
Blunt traumatic thoracic aortic rupture is a life-threatening surgical emergency associated with high mortality and morbidity. The recent development of endovascular stent-graft prostheses offers a potentially less invasive alternative to open chest surgery, especially in patients with associated injuries. We sought to compare the results of conventional surgical repair and endovascular treatment of traumatic aortic rupture in a single center.
From July 1998 to January 2004, 20 patients with acute blunt traumatic aortic rupture underwent treatment at our institution. All patients had a lesion limited to the isthmus, and associated injuries. Initial management included fluid resuscitation, treatment of other severe associated lesions, and strict monitoring of blood pressure. Eleven patients (9 men, 2 women; mean age, 32 years) underwent surgical repair, including direct suturing in 6 patients and graft interposition in 5 patients. Ten patients were operated on with cardiopulmonary support (left bypass with centrifugal pump, n = 2; extracorporeal circulation, n = 8). The delay between trauma and surgery was 2.6 days (range, 0-21 days). Nine patients (8 men, 1 woman; mean age, 32 years) underwent endovascular treatment with commercially available devices (Excluder, n = 2; Talent, n = 7). In all patients 1 stent graft was deployed. In 2 patients the left subclavian artery was intentionally covered with the device. The delay between trauma and endovascular treatment was 17.8 days (range, 1-68 days).
One patient in the surgical group (9.1%) died during the intervention. Three surgical complications occurred in 3 patients (27%), including left phrenic nerve palsy (n = 1), left-sided recurrent nerve palsy (n = 1), and hemopericardium 16 days after surgery that required a repeat intervention (n = 1). No patient in this group had paraplegia. In the endovascular group successful stent-graft deployment was achieved in all patients, with no conversion to open repair. No patient died, and no procedure-related complications, including paraplegia, occurred in this group. Control computed tomography scans obtained within 7 days after endovascular treatment showed exclusion of pseudoaneurysm in all cases. Length of follow-up for endovascular treatment ranged from 3 to 41 months (mean, 15.1 months). Computed tomography scans obtained 3 months after endovascular treatment showed complete disappearance of pseudoaneurysm in all patients.
In the treatment of blunt traumatic thoracic aortic rupture, the immediate outcome in patients who receive endovascular stent grafts appears to be at least as good as observed after conventional surgical repair. Long-term follow-up is necessary to assess long-term effectiveness of such management.
钝性创伤性胸主动脉破裂是一种危及生命的外科急症,死亡率和发病率都很高。血管内支架移植物假体的最新发展为开胸手术提供了一种潜在的侵入性较小的替代方案,尤其是对于伴有其他损伤的患者。我们试图在单一中心比较创伤性主动脉破裂的传统手术修复和血管内治疗的结果。
1998年7月至2004年1月,20例急性钝性创伤性主动脉破裂患者在我院接受治疗。所有患者的病变均局限于峡部,并伴有其他损伤。初始治疗包括液体复苏、治疗其他严重的相关病变以及严格监测血压。11例患者(9例男性,2例女性;平均年龄32岁)接受了手术修复,其中6例患者进行了直接缝合,5例患者进行了移植物植入。10例患者在心肺支持下进行手术(2例使用离心泵左心旁路,8例使用体外循环)。创伤与手术之间的延迟时间为2.6天(范围为0 - 21天)。9例患者(8例男性,1例女性;平均年龄32岁)使用市售装置(Excluder,2例;Talent,7例)进行了血管内治疗。所有患者均植入了1个支架移植物。2例患者的左锁骨下动脉被该装置有意覆盖。创伤与血管内治疗之间的延迟时间为17.8天(范围为1 - 68天)。
手术组中有1例患者(9.1%)在干预过程中死亡。3例患者(27%)发生了3种手术并发症,包括左膈神经麻痹(1例)、左侧喉返神经麻痹(1例)以及术后16天发生血心包需要再次干预(1例)。该组中没有患者发生截瘫。在血管内治疗组中,所有患者均成功植入了支架移植物,无需转为开放修复。该组中没有患者死亡,也没有发生包括截瘫在内的与手术相关的并发症。血管内治疗后7天内进行的对照计算机断层扫描显示,所有病例的假性动脉瘤均被排除。血管内治疗的随访时间为3至41个月(平均15.1个月)。血管内治疗后3个月进行的计算机断层扫描显示,所有患者假性动脉瘤均完全消失。
在钝性创伤性胸主动脉破裂的治疗中,接受血管内支架移植物治疗的患者的即时结果似乎至少与传统手术修复后的结果一样好。需要长期随访以评估这种治疗方法的长期有效性。