• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

钆用于对碘化造影剂过敏患者的脊柱手术——127例手术经验

Gadolinium use in spine procedures for patients with allergy to iodinated contrast--experience of 127 procedures.

作者信息

Safriel Y, Ali M, Hayt M, Ang R

机构信息

Center for Diagnostic Imaging, Waite Park, MN, USA.

出版信息

AJNR Am J Neuroradiol. 2006 Jun-Jul;27(6):1194-7.

PMID:16775262
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8133924/
Abstract

BACKGROUND AND PURPOSE

To review the safety and efficacy of gadolinium as a contrast agent in spine pain management procedures in patients who are at high risk for a contrast reaction and are therefore unacceptable candidates for the use of standard nonionic contrast.

METHODS

We reviewed our records over a 4-year period of interlaminar and foraminal epidural steroid injections, nerve blocks, facet injections, intercostal blocks, and diskograms in the lumbar, thoracic, and cervical spine for cases in which patients had allergies that made them unsuitable candidates for standard nonionic contrast and where gadolinium was used to confirm needle tip placement before injection of medication.

RESULTS

Ninety-two patients underwent 127 procedures. A spinal needle was used in all but 7 procedures. All patients were outpatients and all were discharged without complication after 20 to 45 minutes with follow-up instructions. No delayed complications were reported. Gadolinium was visualized by using portable C-arm fluoroscopy in vivo allowing for confirmation of needle tip location. For epidural steroid injection, the gadolinium dose ranged from 1 to 5 mL, nerve blocks from 0.2 to 1 mL per level, facet injections from 0.2 to 0.5 mL per level, intercostal blocks used 0.5 mL, and diskograms from 1.5 to 7.5 mL per level. The highest dose received by 1 patient was an intradiskal 15.83 mL during a 3-level diskogram.

CONCLUSION

Gadolinium seems to be a safe alternative to standard nonionic contrast in spine pain management procedures in those patients considered to be at high risk for a contrast reaction.

摘要

背景与目的

回顾钆作为造影剂在脊柱疼痛治疗手术中的安全性和有效性,这些患者发生造影剂反应的风险较高,因此不适合使用标准非离子型造影剂。

方法

我们回顾了4年期间在腰椎、胸椎和颈椎进行的椎板间和椎间孔硬膜外类固醇注射、神经阻滞、小关节注射、肋间阻滞和椎间盘造影的记录,这些病例中的患者存在过敏反应,使其不适合使用标准非离子型造影剂,并且在注射药物前使用钆来确认针尖位置。

结果

92例患者接受了127次手术。除7次手术外,所有手术均使用了脊柱穿刺针。所有患者均为门诊患者,术后20至45分钟均出院,无并发症,并给予了随访指导。未报告延迟并发症。通过便携式C形臂荧光透视在体内观察到钆,从而确认了针尖位置。对于硬膜外类固醇注射,钆的剂量范围为1至5毫升,神经阻滞每节段为0.2至1毫升,小关节注射每节段为0.2至0.5毫升,肋间阻滞使用0.5毫升,椎间盘造影每节段为1.5至7.5毫升。1例患者在3节段椎间盘造影期间接受的最高剂量为椎间盘内15.83毫升。

结论

对于那些被认为发生造影剂反应风险较高的患者,在脊柱疼痛治疗手术中,钆似乎是标准非离子型造影剂的一种安全替代品。

相似文献

1
Gadolinium use in spine procedures for patients with allergy to iodinated contrast--experience of 127 procedures.钆用于对碘化造影剂过敏患者的脊柱手术——127例手术经验
AJNR Am J Neuroradiol. 2006 Jun-Jul;27(6):1194-7.
2
Gadolinium use in spine pain management procedures for patients with contrast allergies: results in 527 procedures.
Cardiovasc Intervent Radiol. 2008 Mar-Apr;31(2):325-31. doi: 10.1007/s00270-007-9192-5. Epub 2007 Oct 16.
3
Use of gadolinium chelate to confirm epidural needle placement in patients with an iodinated contrast reaction.使用钆螯合物确认碘造影剂过敏患者的硬膜外穿刺针位置。
Skeletal Radiol. 2007 Apr;36(4):301-7. doi: 10.1007/s00256-006-0228-8. Epub 2006 Dec 23.
4
Hidden risk of gadolinium-based contrast agents during interventional pain medicine procedures: a retrospective chart review.介入疼痛医学治疗过程中钆基造影剂的潜在风险:回顾性图表分析。
Reg Anesth Pain Med. 2024 Oct 8;49(10):751-756. doi: 10.1136/rapm-2023-104952.
5
Absence of Iodinated Contrast Hypersensitivity and Characterization of Gadolinium Utilization in an Interventional Pain Population.碘对比剂过敏反应的缺失与介入性疼痛人群中钆利用情况的特征。
Pain Pract. 2021 Feb;21(2):184-189. doi: 10.1111/papr.12947. Epub 2020 Sep 25.
6
Epidurography and therapeutic epidural injections: technical considerations and experience with 5334 cases.硬膜外造影术及治疗性硬膜外注射:技术要点及5334例经验
AJNR Am J Neuroradiol. 1999 Apr;20(4):697-705.
7
Incidence of intravascular penetration in transforaminal cervical epidural steroid injections.经椎间孔颈椎硬膜外类固醇注射时血管内穿刺的发生率。
Spine (Phila Pa 1976). 2003 Jan 1;28(1):21-5. doi: 10.1097/00007632-200301010-00007.
8
Visualization of spinal injection procedures using gadolinium contrast.
Spine (Phila Pa 1976). 2003 Dec 1;28(23):E496-8. doi: 10.1097/01.BRS.0000099096.63222.CF.
9
CT Fluoroscopy-Guided Interlaminar Epidural Steroid Injections in the Cervical Spine: Rate of Nontarget Injection Into the Retrodural Space of Okada.CT 透视引导下颈椎椎管内硬膜外类固醇注射:Okada 法非靶区注射入硬膜后间隙的发生率。
AJR Am J Roentgenol. 2018 Aug;211(2):426-431. doi: 10.2214/AJR.18.19606. Epub 2018 May 29.
10
Technique for CT fluoroscopy-guided cervical interlaminar steroid injections.CT 透视引导下颈椎间孔内类固醇注射技术。
AJR Am J Roentgenol. 2012 Mar;198(3):675-7. doi: 10.2214/AJR.11.6809.

引用本文的文献

1
Testicular varicocele embolization using CO2, gadolinium and lipiodol as contrast agents in a patient with an iodinated contrast allergy.在一名对碘化造影剂过敏的患者中,使用二氧化碳、钆和碘油作为造影剂进行睾丸精索静脉曲张栓塞术。
Radiol Case Rep. 2025 Jul 28;20(10):5205-5209. doi: 10.1016/j.radcr.2025.06.107. eCollection 2025 Oct.
2
Are gadolinium-based contrast media safe alternatives to iodinated contrast agents for the safe performance of spinal injection procedures?对于脊柱注射程序的安全实施,钆基造影剂是碘化造影剂的安全替代品吗?
Interv Pain Med. 2025 Jan 2;4(1):100538. doi: 10.1016/j.inpm.2024.100538. eCollection 2025 Mar.
3
Iodinated contrast media shortage: Insights and guidance from two major public hospitals.碘对比剂短缺:两家大型公立医院的见解和指导。
J Med Imaging Radiat Oncol. 2022 Oct;66(7):946-956. doi: 10.1111/1754-9485.13444. Epub 2022 Jun 10.
4
MR epidurography: distribution of injectate at caudal epidural injection.磁共振脊髓造影:尾端硬膜外注射时注射液的分布情况
Skeletal Radiol. 2015 Apr;44(4):565-71. doi: 10.1007/s00256-014-1963-x. Epub 2014 Aug 2.
5
High-resolution magnetic resonance-guided posterior femoral cutaneous nerve blocks.高分辨率磁共振引导下股后皮神经阻滞。
Skeletal Radiol. 2013 Apr;42(4):579-86. doi: 10.1007/s00256-012-1553-8. Epub 2012 Dec 20.
6
Safety of 1000 CT-guided steroid injections with air used to localize the epidural space.1000 例 CT 引导下使用空气定位硬膜外腔的类固醇注射的安全性。
AJNR Am J Neuroradiol. 2011 Oct;32(9):E175-7. doi: 10.3174/ajnr.A2316. Epub 2011 Jan 13.
7
Complications and pitfalls of lumbar interlaminar and transforaminal epidural injections.腰椎间和椎间孔硬膜外注射的并发症和陷阱。
Curr Rev Musculoskelet Med. 2008 Dec;1(3-4):212-22. doi: 10.1007/s12178-008-9035-2. Epub 2008 Aug 15.
8
Use of gadolinium chelate to confirm epidural needle placement in patients with an iodinated contrast reaction.使用钆螯合物确认碘造影剂过敏患者的硬膜外穿刺针位置。
Skeletal Radiol. 2007 Apr;36(4):301-7. doi: 10.1007/s00256-006-0228-8. Epub 2006 Dec 23.

本文引用的文献

1
Incorrect needle position during lumbar epidural steroid administration: inaccuracy of loss of air pressure resistance and requirement of fluoroscopy and epidurography during needle insertion.腰椎硬膜外类固醇注射时的针位置不正确:空气压力阻力消失的不准确以及在进针过程中需要荧光透视和硬膜造影。
AJNR Am J Neuroradiol. 2005 Mar;26(3):502-5.
2
Gadolinium diskography.钆椎间盘造影术
AJNR Am J Neuroradiol. 2004 Nov-Dec;25(10):1824-7.
3
Gadolinium-enhanced CT angiography of the circle of Willis and neck.Willis环及颈部的钆增强CT血管造影术。
AJNR Am J Neuroradiol. 2004 Jun-Jul;25(6):969-72.
4
Fluoroscopically guided lumbar transformational epidural steroid injections in degenerative lumbar stenosis: an outcome study.荧光镜引导下腰椎退变狭窄症的经椎间孔硬膜外类固醇注射:一项疗效研究。
Am J Phys Med Rehabil. 2002 Dec;81(12):898-905. doi: 10.1097/00002060-200212000-00003.
5
Intrathecal gadolinium (gadopentetate dimeglumine) enhanced magnetic resonance myelography and cisternography: results of a multicenter study.鞘内注射钆(钆喷酸葡胺)增强磁共振脊髓造影和脑池造影:一项多中心研究的结果。
Invest Radiol. 2002 Mar;37(3):152-9. doi: 10.1097/00004424-200203000-00008.
6
Safety of gadolinium contrast agent in hemodialysis patients.钆造影剂在血液透析患者中的安全性。
Acta Radiol. 2001 May;42(3):339-41. doi: 10.1080/028418501127346756.
7
Serial gadolinium-DTPA of spinal cord MRI in multiple sclerosis: triple vs. single dose.多发性硬化症脊髓磁共振成像中钆喷酸葡胺的系列应用:三倍剂量与单剂量对比
Magn Reson Imaging. 2000 Nov;18(9):1183-6. doi: 10.1016/s0730-725x(00)00191-0.
8
The effect of nerve-root injections on the need for operative treatment of lumbar radicular pain. A prospective, randomized, controlled, double-blind study.神经根注射对腰椎神经根性疼痛手术治疗需求的影响。一项前瞻性、随机、对照、双盲研究。
J Bone Joint Surg Am. 2000 Nov;82(11):1589-93. doi: 10.2106/00004623-200011000-00012.
9
Epidurography and therapeutic epidural injections: technical considerations and experience with 5334 cases.硬膜外造影术及治疗性硬膜外注射:技术要点及5334例经验
AJNR Am J Neuroradiol. 1999 Apr;20(4):697-705.
10
Back to the future: epidurography.回到未来:硬膜外造影术。
AJNR Am J Neuroradiol. 1999 Apr;20(4):537.