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两例与克兰费尔特综合征相关的脊髓内生殖细胞瘤患者:病例报告及文献综述

Two patients with intraspinal germinoma associated with Klinefelter syndrome: case report and review of the literature.

作者信息

Nakata Y, Yagishita A, Arai N

机构信息

Department of Neuroradiology, Tokyo Metropolitan Neurological Hospital, 2-6-1 Musashi-dai, Fuchu, Tokyo 183-0042, Japan.

出版信息

AJNR Am J Neuroradiol. 2006 Jun-Jul;27(6):1204-10.

Abstract

We report 2 cases of intraspinal germinoma associated with Klinefelter syndrome. In one patient, spinal cord atrophy was observed at the upper and lower ends of the intraspinal tumor. Brain atrophy was observed in both cases. Germinoma should be included in the differential diagnosis if an intraspinal tumor is observed in a patient with Klinefelter syndrome.

摘要

我们报告2例与克兰费尔特综合征相关的脊髓内生殖细胞瘤。在1例患者中,在脊髓内肿瘤的上下两端观察到脊髓萎缩。2例均观察到脑萎缩。如果在克兰费尔特综合征患者中观察到脊髓内肿瘤,应将生殖细胞瘤纳入鉴别诊断。

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本文引用的文献

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Intramedullary spinal cord germinoma expresses the protooncogene c-kit.
Acta Neurochir (Wien). 2005 Mar;147(3):303-8; discussion 308. doi: 10.1007/s00701-004-0450-x.
3
De novo germinoma in the brain in association with Klinefelter's syndrome: case report and review of the literature.
Surg Neurol. 2003 Dec;60(6):553-8; discussion 559. doi: 10.1016/s0090-3019(03)00454-3.

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