Murphy E M A, Farquharson S M, Moran B J
Colorectal Research Unit, North Hampshire Hospital, Aldermaston Road, Basingstoke RG24 9NA, UK.
Br J Surg. 2006 Jul;93(7):783-92. doi: 10.1002/bjs.5385.
Appendiceal neoplasms are rare and most present unexpectedly as acute appendicitis. The classification and management are confusing, and there are few substantial reports in the literature.
A systematic literature review was performed to access relevant publications on the presentation, pathology and management of appendiceal tumours.
Appendiceal tumours account for 0.4 to 1 per cent of all gastrointestinal tract malignancies and are found in 0.7 to 1.7 per cent of appendicectomy specimens. Carcinoid tumours are most common. Most are cured by simple appendicectomy if the tumour is less than 2 cm in size and does not involve the resection margin or mesoappendix. Epithelial tumours may present with, or in time develop, pseudomyxoma peritonei, the optimal management of which involves complete tumour resection and intraperitoneal chemotherapy, usually available only in specialized centres.
Suggested algorithms for the management of unexpected appendiceal tumours are provided. Recommendations are made for follow-up of patients with a perforated appendiceal epithelial tumour.
阑尾肿瘤较为罕见，多数以急性阑尾炎的形式意外出现。其分类和治疗方法尚不明确，文献中也鲜有详尽报道。
进行系统的文献综述，以获取有关阑尾肿瘤的表现、病理及治疗的相关出版物。
阑尾肿瘤占所有胃肠道恶性肿瘤的0.4%至1%，在阑尾切除标本中占0.7%至1.7%。类癌肿瘤最为常见。如果肿瘤小于2厘米且未累及手术切缘或阑尾系膜，多数通过单纯阑尾切除术即可治愈。上皮性肿瘤可能会出现或随时间发展为腹膜假黏液瘤，其最佳治疗方法包括完整切除肿瘤和腹腔内化疗，通常只有在专业中心才能进行。
提供了针对意外发现的阑尾肿瘤的建议治疗方案。对阑尾上皮性肿瘤穿孔患者的随访提出了建议。
