Saby R C, Mardelle V, Gil C, Petrognani R, Mion G, Carpentier J P
Département d'anesthésie-réanimation-urgences, Hôpital d'Instruction des Armées Laveran, BP 50, 13998 Marseille-Armées.
Med Trop (Mars). 2006 Apr;66(2):125-9.
Ketamine is an anesthetic drug of choice in tropical zones. In addition to excellent pharmocologic properties and low cost, it offers the possibility of using a variety of administration routes and of performing invasive procedures with spontaneous ventilation. Adverse psychodysleptic effects can be prevented by association with midazolam or propofol. Hypersalivation can be prevented with atropine. Recent experience has shown that thanks to its antihyperalgesic effects ketamine can be used for postoperative analgesia at doses ten times lower than for anesthesia.
氯胺酮是热带地区麻醉药物的首选。除了具有出色的药理特性和低成本外，它还提供了多种给药途径的可能性，并且可以在自主通气的情况下进行侵入性操作。与咪达唑仑或丙泊酚联合使用可预防不良精神错乱效应。使用阿托品可预防唾液分泌过多。最近的经验表明，由于其抗痛觉过敏作用，氯胺酮可用于术后镇痛，其剂量比麻醉剂量低十倍。
