Okome-Nkoumou M, Boguikouma J B, Kombila M
Département de médecine interne et spécialités médicales, Université des Sciences de la Sante , Libreville, Gabon.
Med Trop (Mars). 2006 Apr;66(2):167-71.
The purpose of this study was to determine the frequencies of opportunistic diseases among AIDS patients at the Jeanne Ebori Foundation (JEF) in Libreville, Gabon. A total 6313 file of patients treated in the internal medicine unit between 1994 and 1998 were analyzed. Findings showed that the main diseases related to AIDS classified according to seroprevalence were as follows: purigo (100%), cerebral toxoplasmosis (100%), oral candidiaisis (88%), bacteremia (87.8%), shingles (84.6%), minor salmonelosis (72%), and tuberclosis. The main diagnoses unrelated to AIDS at the JEF according to seroprevalene were typhoid (9.4%), common pneumonia (28%), bacterial meningitis (26.3%, hepatitis B (20.0%), and malaria (14%). In addition to these diseases there were nine cases of Kaposi's sarcoma, four cases of isosporosis, two cases of cryptococcosis, two cases of herpes Varicella, one case of cryptosporidiosis, and one case of isosporosis. The incidence of opportunistic disease was high in our study and must be taken in drug procurement.
本研究的目的是确定加蓬利伯维尔珍妮·埃博里基金会（JEF）艾滋病患者中机会性疾病的发生率。对1994年至1998年在内科接受治疗的6313份患者病历进行了分析。结果显示，根据血清阳性率分类的与艾滋病相关的主要疾病如下：脓疱疹（100%）、脑弓形虫病（100%）、口腔念珠菌病（88%）、菌血症（87.8%）、带状疱疹（84.6%）、轻度沙门氏菌病（72%）和结核病。根据血清阳性率，JEF与艾滋病无关的主要诊断为伤寒（9.4%）、普通肺炎（28%）、细菌性脑膜炎（26.3%）、乙型肝炎（20.0%）和疟疾（14%）。除这些疾病外，还有9例卡波西肉瘤、4例等孢球虫病、2例隐球菌病、2例水痘带状疱疹、1例隐孢子虫病和1例等孢球虫病。在我们的研究中，机会性疾病的发生率很高，在药物采购中必须予以考虑。
