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颈椎前路椎间融合术后钛翼形椎间融合器下沉:2年随访研究

Subsidence of the wing titanium cage after anterior cervical interbody fusion: 2-year follow-up study.

作者信息

Schmieder Kirsten, Wolzik-Grossmann Markus, Pechlivanis Ioannis, Engelhardt Martin, Scholz Martin, Harders Albrecht

机构信息

Department of Neurosurgery, Ruhr-University Bochum, Germany.

出版信息

J Neurosurg Spine. 2006 Jun;4(6):447-53. doi: 10.3171/spi.2006.4.6.447.

DOI:10.3171/spi.2006.4.6.447
PMID:16776355
Abstract

OBJECT

Cage subsidence occurs after anterior cervical discectomy and fusion (ACDF). The aim of this prospective study was to evaluate subsidence and total segmental height after implantation of a newly designed Wing titanium cage. Furthermore, alignment of the entire cervical spine was analyzed 2 years after surgery.

METHODS

Fifty-four patients (26 women and 28 men) whose mean age was 48.3 years underwent ACDF. Follow-up examinations were performed at discharge and 6, 12, and 24 months postoperatively by an independent investigator. The clinical course was evaluated using the visual analog pain scale and the Prolo scales. Measurements of subsidence and total segmental height were conducted, and the alignment of the entire cervical spine was classified using two methods. In 54 patients 64 levels were fused. The patients noted a significant reduction of pain, and scores on both Prolo scales were significantly improved. At the 2-year follow-up examination, subsidence was present in 30 of the 67 fused segments. There was a statistically significant correlation between subsidence and the presence of posterior spondylosis at the initial surgery. Furthermore, there was a significant correlation between reduction of total segmental height and the presence of subsidence; however, subsidence did not prevent the development of a solid bone arthrodesis (fusion rate 98%) or have an adverse effect on the alignment of the cervical spine.

CONCLUSIONS

Titanium Wing cage-augmented ACDF was associated with comparatively good long-term results. Subsidence was present but did not cause clinical complications. Furthermore, radiological studies demonstrated that the physiological alignment of the cervical spine was preserved and a solid bone arthrodesis was present at 2 years after surgery.

摘要

目的

颈椎前路椎间盘切除融合术(ACDF)后会发生椎间融合器下沉。本前瞻性研究的目的是评估新型Wing钛制椎间融合器植入后的下沉情况和节段总高度。此外,在术后2年分析整个颈椎的对线情况。

方法

54例患者(26例女性和28例男性),平均年龄48.3岁,接受了ACDF手术。由一名独立研究者在出院时以及术后6、12和24个月进行随访检查。使用视觉模拟疼痛量表和普罗洛量表评估临床过程。测量下沉情况和节段总高度,并使用两种方法对整个颈椎的对线情况进行分类。54例患者共融合了64个节段。患者的疼痛明显减轻,普罗洛量表的评分均显著改善。在2年的随访检查中,67个融合节段中有30个出现下沉。下沉与初次手术时后纵韧带骨化的存在之间存在统计学上的显著相关性。此外,节段总高度的降低与下沉的存在之间存在显著相关性;然而,下沉并未妨碍坚固的骨融合的形成(融合率98%),也未对颈椎的对线产生不利影响。

结论

钛制Wing椎间融合器增强的ACDF具有相对较好的长期效果。存在下沉情况,但未引起临床并发症。此外,影像学研究表明,术后2年颈椎的生理对线得以保留,且存在坚固的骨融合。

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