Koren Gideon, Moretti Myla, Kapur Bhushan
The Motherisk Program, Hospital for Sick Children, Toronto ON.
J Obstet Gynaecol Can. 2006 Apr;28(4):299-301. doi: 10.1016/S1701-2163(16)32135-1.
A newborn infant whose mother had used venlafaxine, a selective inhibitor of both norepinephrine and serotonin reuptake, throughout pregnancy exhibited signs consistent with the norepinephrine and serotonin reuptake withdrawal syndrome. Is it possible that mother's milk can help mitigate the effects of norepinephrine and serotonin reuptake withdrawal? Pharmacokinetic analysis and review of the only published case with active treatment of a baby with venlafaxine suggest that breastfeeding may mitigate the neonatal withdrawal syndrome.
一名新生儿的母亲在整个孕期都使用了文拉法辛（一种去甲肾上腺素和5-羟色胺再摄取的选择性抑制剂），该新生儿表现出与去甲肾上腺素和5-羟色胺再摄取戒断综合征相符的症状。母乳有可能有助于减轻去甲肾上腺素和5-羟色胺再摄取戒断的影响吗？对唯一一篇已发表的关于用文拉法辛积极治疗婴儿的病例进行的药代动力学分析和综述表明，母乳喂养可能会减轻新生儿戒断综合征。
