Marcoux Danielle, Nadeau Karine, McCuaig Catherine, Powell Julie, Oligny Luc L
Division of Dermatology, Department of Pediatrics, CHU Mère-Enfant Sainte-Justine, Cote Ste-Catherine, Montréal, Quebec.
Pediatr Dermatol. 2006 May-Jun;23(3):199-207. doi: 10.1111/j.1525-1470.2006.00218.x.
The objectives of this study were to delineate the clinical characteristics of a hospital-referred pediatric population infected with anogenital warts and to investigate the possible relationships between human papillomavirus types and the identified clinical characteristics. Over a 7-year period, 72 patients under the age of 12 years were seen at our dermatology clinic for anogenital warts, corresponding to a prevalence of 1.7/1000 in our patient population. Sixty-four percent (46/72) were girls. Congenital, prenatal, ascending infections occurred in two subjects. The onset of anogenital warts occurred before age 2 in 28% and between 2 and 6 years of age in 62% of children and tended to be younger in boys. We identified unusual cutaneomucosal serotypes human papillomavirus 7 and 57 (three and eight instances, respectively). The modes of transmission of anogenital warts in children cannot be identified either by the clinical appearance of the lesions or by human papillomavirus typing. We conclude that the best way to identify possible sexual abuse is still by history taking, careful assessment of the socio-clinical context, and physical examination.
本研究的目的是描述转诊至我院的感染肛门生殖器疣的儿科人群的临床特征，并调查人乳头瘤病毒类型与已确定的临床特征之间的可能关系。在7年期间，我院皮肤科门诊共诊治了72例12岁以下的肛门生殖器疣患者，在我院患者人群中的患病率为1.7/1000。64%（46/72）为女孩。两名患者发生了先天性、产前、上行性感染。28%的儿童肛门生殖器疣发病于2岁之前，62%发病于2至6岁之间，且男孩发病年龄往往更小。我们鉴定出了不常见的皮肤黏膜血清型人乳头瘤病毒7型和57型（分别为3例和8例）。儿童肛门生殖器疣的传播方式无法通过病变的临床表现或人乳头瘤病毒分型来确定。我们得出结论，识别可能的性虐待的最佳方法仍然是通过病史采集、对社会临床背景的仔细评估和体格检查。
