Dinleyici Meltem, Saracoglu Nurhan, Eren Makbule, Kiliç Ömer, Ciftci Evrim, Dinleyici Ener Cagri, Sag Cigdem, Kara Ates
Deprtments of Social Pediatrics, Eskisehir Osmangazi University, Turkey
Dermatology, Eskisehir Osmangazi University, Turkey
Dermatol Reports. 2015 Dec 3;7(3):6134. doi: 10.4081/dr.2015.6134.
Anogenital warts related to human papillomavirus (HPV) have been observed in children. Definition of the transmission mode, therapy, and follow-up for long term potential complications is important. A 27-month old girl was admitted with multiple pedunculated red-purple colored cauliflower-like lesions of 1.5 years duration. Clinical/histopathological and microbiological diagnosis was condyloma acuminate due to HPV type 16. After 12 weeks of imiquimod 5% cream application (pea-sized) overnight three times per week, the perianal warts had completely disappeared. The mode of transmission of HPV 16 in our case was probably horizontal, related to the sharing of common personal hygiene items in the women's shelter. We report herein the case of an infant living in a women's shelter with giant condyloma acuminata due to HPV 16, which was successfully treated with topical imiquimod therapy. This patient should be followed up for recurrence and potential malignant lesions related to HPV type 16.
儿童中已观察到与人类乳头瘤病毒（HPV）相关的肛门生殖器疣。明确传播方式、治疗方法以及对长期潜在并发症的随访很重要。一名27个月大的女童因持续1.5年的多个带蒂红紫色菜花状病变入院。临床/组织病理学和微生物学诊断为16型HPV引起的尖锐湿疣。每周三次在夜间涂抹5%咪喹莫特乳膏（豌豆大小），持续12周后，肛周疣完全消失。在我们的病例中，16型HPV的传播方式可能是水平传播，与妇女庇护所中个人卫生用品的共用有关。我们在此报告一例居住在妇女庇护所的婴儿因16型HPV感染患有巨大尖锐湿疣，经局部咪喹莫特治疗成功治愈的病例。该患者应随访是否复发以及与16型HPV相关的潜在恶性病变。
