抑郁症康复中的认知与社会功能：基于人群的三年随访结果
Cognitive and social functioning in recovery from depression: results from a population-based three-year follow-up.
作者信息
Airaksinen Eija, Wahlin Ake, Larsson Maria, Forsell Yvonne
机构信息
Department of Public Health Sciences, Division of Social Medicine, Karolinska Institutet, Stockholm, Sweden.
出版信息
J Affect Disord. 2006 Nov;96(1-2):107-10. doi: 10.1016/j.jad.2006.05.004. Epub 2006 Jun 19.
BACKGROUND
This study prospectively examined cognitive and social functioning in recovery from depression using participants sampled from the general population.
METHOD
Seventy-six depressed persons fulfilling (n=41) and not fulfilling (n=35) the criteria for DSM-IV depression at a three-year follow-up were compared with respect to episodic memory performance and social functioning at baseline (T1), at follow-up (T2) and change across time.
RESULTS
The groups did not differ in episodic memory performance either at T1, T2 or in residual change. However, the groups differed in social functioning at T2 and in residual change indicating improved social functioning in the recovered group.
LIMITATION
The absence of a healthy control group at follow-up.
CONCLUSION
Despite the symptomatic improvement and improved social functioning, cognitive functioning does not follow this general recovery trend, at least not in the three-year interval examined.
背景
本研究通过从普通人群中抽样选取参与者，前瞻性地考察了抑郁症康复过程中的认知和社会功能。
方法
将76名抑郁症患者分为两组，一组（n = 41）在三年随访时符合DSM-IV抑郁症标准，另一组（n = 35）不符合该标准，比较两组在基线（T1）、随访时（T2）的情景记忆表现和社会功能，以及随时间的变化情况。
结果
两组在T1、T2时的情景记忆表现或残留变化方面均无差异。然而，两组在T2时的社会功能以及残留变化方面存在差异，表明康复组的社会功能有所改善。
局限性
随访时未设置健康对照组。
结论
尽管症状有所改善且社会功能有所提升，但认知功能并未遵循这种总体康复趋势，至少在所考察的三年时间间隔内如此。
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