Churg J
Department of Pathology, Mount Sinai School of Medicine, New York, NY.
Am J Kidney Dis. 1991 Aug;18(2):148-53. doi: 10.1016/s0272-6386(12)80871-7.
Since the original description of periarteritis nodosa (PAN) in 1866, the number of recognized forms of so-called idiopathic vasculitis has risen to about a dozen. Their relation to each other and their nature remain unclear, although the recent discovery of antineutrophil cytoplasmic autoantibodies (ANCA) promises a clue to the origin of at least some of them, particularly Wegener's granulomatosis (WG) and perhaps also Churg-Strauss syndrome (CSS). On the other hand, PAN appears to be a nonspecific syndrome of various etiologies.
自1866年首次描述结节性多动脉炎（PAN）以来，所谓特发性血管炎的已识别类型数量已增至约十二种。尽管最近发现抗中性粒细胞胞浆自身抗体（ANCA）有望为至少其中一些类型（特别是韦格纳肉芽肿病（WG），或许还有变应性肉芽肿性血管炎（CSS））的起源提供线索，但它们彼此之间的关系及其本质仍不清楚。另一方面，PAN似乎是一种病因各异的非特异性综合征。
