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[在比利牛斯地区获得感染的免疫功能正常者中的内脏利什曼病]

[Visceral leishmaniasis in an immunocompetent subject, acquired in the Pyrenees region].

作者信息

Malvy Denis, Djossou Félix, Ibanez C, Vatan Rémy, Longy-Boursier Maïté, Le Bras Michel

机构信息

Fédération de médecine interne, maladies infectieuses et tropicales, Hôpital Saint-André, Bordeaux (33).

出版信息

Presse Med. 2006 Jun;35(6 Pt 1):987-8. doi: 10.1016/s0755-4982(06)74735-2.

Abstract

INTRODUCTION

Visceral leishmaniasis can develop in immunocompetent subjects exposed to a risk of infestation during physical activities outdoors.

CASE

A 35-year-old woman was hospitalized for impaired health status with fever, hepatomegaly, splenomegaly, and pancytopenia, which worsened during her stay. Leishmaniasis was finally diagnosed, based on serologic testing and the finding of Leishmania infantum in the sternal aspiration. Eight months earlier, she had spent two weeks at a lake in the Pyrenees. Treatment with meglumine antimoniate was efficacious.

COMMENTS

This case is original because of the extent of the organomegaly and its onset after vacation in an area far from those where it is thought to be endemic.

摘要

引言

内脏利什曼病可发生于在户外体育活动中面临感染风险的免疫功能正常的个体。

病例

一名35岁女性因健康状况受损入院,伴有发热、肝肿大、脾肿大和全血细胞减少,住院期间病情加重。最终根据血清学检测及胸骨穿刺发现婴儿利什曼原虫确诊为利什曼病。八个月前,她在比利牛斯山脉的一个湖边度过了两周。葡甲胺锑酸盐治疗有效。

评论

该病例具有独特性,因其器官肿大程度以及在远离该病流行地区度假后发病。

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