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Visceral leishmaniasis without fever in an 11-month-old infant: a rare clinical feature of Kala-azar.

作者信息

Sayyahfar Shirin, Ansari Shahla, Mohebali Mehdi, Behnam Babak

机构信息

Department of Pediatrics, Ali Asghar Children Hospital, Iran University of Medical Sciences, Tehran, Iran.

Department of Parasitology and Mycology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.

出版信息

Korean J Parasitol. 2014 Apr;52(2):189-91. doi: 10.3347/kjp.2014.52.2.189. Epub 2014 Apr 18.


DOI:10.3347/kjp.2014.52.2.189
PMID:24850963
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4028457/
Abstract

Visceral leishmaniasis or kala-azar is an endemic parasitic disease in some parts of the world which is characterized by fever, splenomegaly, and pancytopenia in most of the cases. Herein we report an 11 month-old male infant with diagnosis of kala-azar who presented with pallor, hepatosplenomegaly, failure to gain weight, and no history of fever. Surprisingly, fever started after beginning of meglumine antimoniate treatment in this patient. As far as we are aware of, this is a rare presentation of visceral leishmaniasis. Therefore, clinicians especially in endemic areas are highly recommended to include kala-azar among differential diagnosis of unexplained anemia without fever to prevent misdiagnosis of this potentially fatal, but treatable condition.

摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0825/4028457/d25c43fd8827/kjp-52-189-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0825/4028457/8059b6eeed1d/kjp-52-189-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0825/4028457/d25c43fd8827/kjp-52-189-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0825/4028457/8059b6eeed1d/kjp-52-189-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0825/4028457/d25c43fd8827/kjp-52-189-g002.jpg

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[1]
Visceral leishmaniasis without fever in an 11-month-old infant: a rare clinical feature of Kala-azar.

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引用本文的文献

[1]
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BMJ Case Rep. 2022-5-23

[2]
A case of visceral leishmaniasis found by left oblique hernia: A case report.

Exp Ther Med. 2020-4

[3]
Development of monoclonal antibodies against axenic amastigotes of strain in Iran: implication for diagnosis of Kala-azar.

Iran J Basic Med Sci. 2018-4

[4]
T cell suppression in the bone marrow of visceral leishmaniasis patients: impact of parasite load.

Clin Exp Immunol. 2017-11-20

[5]
Leishmaniasis as a Neglected Cause of Isolated Lymphadenopathy: A Case Report.

Iran J Public Health. 2016-7

[6]
Comparison of hematological aspects: Visceral leishmaniasis and healthy children.

Trop Parasitol. 2015

本文引用的文献

[1]
Downregulation of Calcineurin Gene Is Associated with Glucantime(®) Resiatance in Leishmania infantum.

Iran J Parasitol. 2013-7

[2]
Visceral leishmaniasis in Iran: Review of the Epidemiological and Clinical Features.

Iran J Parasitol. 2013-7

[3]
Overexpression of ubiquitin and amino acid permease genes in association with antimony resistance in Leishmania tropica field isolates.

Korean J Parasitol. 2013-8

[4]
Identification of antimony resistance markers in Leishmania tropica field isolates through a cDNA-AFLP approach.

Exp Parasitol. 2013-8-6

[5]
Leishmaniasis: clinical syndromes and treatment.

QJM. 2013-6-5

[6]
Visceral leishmaniasis mimicking autoimmune hepatitis, primary biliary cirrhosis, and systemic lupus erythematosus overlap.

Korean J Parasitol. 2012-6

[7]
Integrated visceral leishmaniasis surveillance system in primary care for children in Meshkin-Shahr district, north-western Islamic Republic of Iran.

East Mediterr Health J. 2010-10

[8]
Combination therapy for visceral leishmaniasis.

Lancet Infect Dis. 2010-3

[9]
A rare presentation of visceral leishmaniasis without fever or splenomegaly in an elderly person.

Eur J Intern Med. 2007-3

[10]
Unresponsiveness to Glucantime treatment in Iranian cutaneous leishmaniasis due to drug-resistant Leishmania tropica parasites.

PLoS Med. 2006-5

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