Sayyahfar Shirin, Ansari Shahla, Mohebali Mehdi, Behnam Babak
Department of Pediatrics, Ali Asghar Children Hospital, Iran University of Medical Sciences, Tehran, Iran.
Department of Parasitology and Mycology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
Korean J Parasitol. 2014 Apr;52(2):189-91. doi: 10.3347/kjp.2014.52.2.189. Epub 2014 Apr 18.
Visceral leishmaniasis or kala-azar is an endemic parasitic disease in some parts of the world which is characterized by fever, splenomegaly, and pancytopenia in most of the cases. Herein we report an 11 month-old male infant with diagnosis of kala-azar who presented with pallor, hepatosplenomegaly, failure to gain weight, and no history of fever. Surprisingly, fever started after beginning of meglumine antimoniate treatment in this patient. As far as we are aware of, this is a rare presentation of visceral leishmaniasis. Therefore, clinicians especially in endemic areas are highly recommended to include kala-azar among differential diagnosis of unexplained anemia without fever to prevent misdiagnosis of this potentially fatal, but treatable condition.
内脏利什曼病或黑热病是世界上某些地区的一种地方性寄生虫病,大多数病例的特征是发热、脾肿大和全血细胞减少。在此,我们报告一名11个月大的男性婴儿,诊断为黑热病,表现为面色苍白、肝脾肿大、体重不增且无发热史。令人惊讶的是,该患者在开始使用葡甲胺锑酸盐治疗后出现发热。据我们所知,这是内脏利什曼病的一种罕见表现。因此,强烈建议临床医生,尤其是在流行地区,将黑热病纳入无发热的不明原因贫血的鉴别诊断中,以防止误诊这种潜在致命但可治疗的疾病。