Yang Chun Chieh, Yeh Chao Hung, Tsai Tsung Chia, Yu Wen Liang
Department of Intensive Care Medicine, Chi-Mei Medical Center, Tainan County, Taiwan.
J Microbiol Immunol Infect. 2006 Jun;39(3):255-8.
Listeria monocytogenes meningitis appears to have increased in incidence. Although most reported cases of listeriosis involve the central nervous system, brain computed tomography is usually normal. Hydrocephalus is a common complication of tuberculous meningitis, which has a high prevalence in Taiwan. However, patients with L. monocytogenes meningitis rarely develop the complication of symptomatic hydrocephalus. We report a patient with L. monocytogenes meningitis who presented with persistent alteration of consciousness after appropriate antimicrobial therapy. Follow-up brain computed tomography revealed acute hydrocephalus. An Ommaya reservoir was implanted, and daily drainage of the cerebrospinal fluid was performed. The patient improved gradually and his mental status recovered completely 4 days later. This case should remind physicians to be aware of the possible occurrence of hydrocephalus in L. monocytogenes meningitis and that prompt cerebrospinal fluid drainage may achieve a good outcome.
单核细胞增生李斯特菌脑膜炎的发病率似乎有所上升。尽管大多数报告的李斯特菌病病例累及中枢神经系统,但脑部计算机断层扫描通常正常。脑积水是结核性脑膜炎的常见并发症,在台湾地区发病率很高。然而,单核细胞增生李斯特菌脑膜炎患者很少出现症状性脑积水并发症。我们报告一例单核细胞增生李斯特菌脑膜炎患者,在接受适当的抗菌治疗后出现持续意识改变。后续脑部计算机断层扫描显示急性脑积水。植入了一个Ommaya储液囊,并每日引流脑脊液。患者逐渐好转,4天后精神状态完全恢复。该病例应提醒医生注意单核细胞增生李斯特菌脑膜炎可能发生脑积水,及时引流脑脊液可能取得良好效果。