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[变应性肉芽肿性血管炎合并多发性神经病]

[Churg-Strauss syndrome complicated by polyneuropathy].

作者信息

Ruzics Csaba, Folyovich András, Fehér Agnes, Arányi Zsuzsanna, Gráf László, Várkonyi Judit

机构信息

Fovárosi Onkormányzat Szent János Kórház, Neurológiai Osztály.

出版信息

Orv Hetil. 2006 May 14;147(19):899-901.

Abstract

Apart from some inherited forms, polyneuropathy is a disorder secondary to systemic diseases. The symptoms of chronic polyneuropathy usually appear some years after the main disease has been diagnosed. However, the acute-subacute form can be the first manifestation of a systemic disease, when its typical clinical features are still absent. The diagnosis of polyneuropathy is based on clinical symptoms and electrophysiologic studies, and it also could be supported by spinal fluid examination and peripheral nerve biopsy. The authors report here a case presenting as Churg-Strauss syndrome complicated with subacute axonal polyneuropathy and eosinophilia characteristic of the disease. Although Churg-Strauss syndrome is rare, it is important to recognise it, because remission depends on immunosuppressive therapy introduced in the early stage.

摘要

除了一些遗传性形式外,多发性神经病是继发于全身性疾病的一种病症。慢性多发性神经病的症状通常在主要疾病被诊断出数年之后出现。然而,急性 - 亚急性形式可能是全身性疾病的首发表现,此时其典型临床特征仍未出现。多发性神经病的诊断基于临床症状和电生理研究,脑脊液检查和周围神经活检也可为其提供支持。作者在此报告一例表现为Churg - Strauss综合征并伴有该疾病特征性的亚急性轴索性多发性神经病和嗜酸性粒细胞增多症的病例。尽管Churg - Strauss综合征罕见,但认识到它很重要,因为缓解取决于早期引入的免疫抑制治疗。

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