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脑磁图描记术(MEG)确定了在对面孔进行经典条件反射的背景下视觉和听觉感觉处理的时间调制。

Magnetoencephalography (MEG) determined temporal modulation of visual and auditory sensory processing in the context of classical conditioning to faces.

作者信息

Dolan R J, Heinze H J, Hurlemann R, Hinrichs H

机构信息

Institute of Neurology, University College London, UK.

出版信息

Neuroimage. 2006 Aug 15;32(2):778-89. doi: 10.1016/j.neuroimage.2006.04.206. Epub 2006 Jun 19.

Abstract

Using magnetoencephalography (MEG), we determined the time course of sensory-evoked modulations during differential aversive conditioning to faces, with an aversive noise event (UCS). Conditioning was associated with the development of a differential event-related waveform peaking at approximately 150 ms. Source analysis indicated the localization of this modulation to ventral occipital regions. In the auditory domain, a modulation of auditory-evoked responses to a probe sound was evident in a late component emerging at approximately 180 ms over sensors in fronto-temporal regions. The findings indicate the time course in processing sensory stimuli can be altered on the basis of their acquired value.

摘要

我们使用脑磁图(MEG)来确定在对脸部进行差别性厌恶条件反射(伴有厌恶噪声事件,即无条件刺激)期间感觉诱发调制的时间进程。条件反射与一个在约150毫秒时达到峰值的差别性事件相关波形的发展有关。源分析表明这种调制定位于枕叶腹侧区域。在听觉领域,对探测声音的听觉诱发反应的调制在额颞区域传感器上方约180毫秒出现的一个晚期成分中很明显。这些发现表明,根据感觉刺激获得的价值,其处理的时间进程可能会发生改变。

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