Dolan R J, Heinze H J, Hurlemann R, Hinrichs H
Institute of Neurology, University College London, UK.
Neuroimage. 2006 Aug 15;32(2):778-89. doi: 10.1016/j.neuroimage.2006.04.206. Epub 2006 Jun 19.
Using magnetoencephalography (MEG), we determined the time course of sensory-evoked modulations during differential aversive conditioning to faces, with an aversive noise event (UCS). Conditioning was associated with the development of a differential event-related waveform peaking at approximately 150 ms. Source analysis indicated the localization of this modulation to ventral occipital regions. In the auditory domain, a modulation of auditory-evoked responses to a probe sound was evident in a late component emerging at approximately 180 ms over sensors in fronto-temporal regions. The findings indicate the time course in processing sensory stimuli can be altered on the basis of their acquired value.
我们使用脑磁图(MEG)来确定在对脸部进行差别性厌恶条件反射(伴有厌恶噪声事件,即无条件刺激)期间感觉诱发调制的时间进程。条件反射与一个在约150毫秒时达到峰值的差别性事件相关波形的发展有关。源分析表明这种调制定位于枕叶腹侧区域。在听觉领域,对探测声音的听觉诱发反应的调制在额颞区域传感器上方约180毫秒出现的一个晚期成分中很明显。这些发现表明,根据感觉刺激获得的价值,其处理的时间进程可能会发生改变。