Güven H Erhan, Pak Isin, Oral Süleyman
Department of General Surgery, Ankara Oncology Research and Training Hospital, Demetevler, Ankara, Turkey.
J Coll Physicians Surg Pak. 2006 Jun;16(6):431-3.
To report the clinical and pathological features and surgical treatment outcomes of patients with granulomatous mastitis.
Case series.
Ankara Oncology Training and Research Hospital, between 1999-2003.
Data of 16 patients with granulomatous mastitis treated surgically by total excision with disease-free margins were reviewed. Patients given additional medical therapy or treated with mastectomy because of the size and extent of the disease were excluded.
The mean age of patients at the time of diagnosis was 31.8 (range: 22-45 years). All patients were diagnosed from the pathological tissue specimens obtained by surgery. Clinical and radiological examinations suggested breast carcinoma in 82.1% patients. Except one patient who developed a fistula from the incision which was treated again with surgery, no other complications were noted, including recurrence of disease during a median follow-up period of 12.8 months (range: 4-30 months).
Although granulomatous mastitis is a rare benign breast disease, it usually mimics breast carcinoma both clinically and radiologically, making the diagnosis difficult and challenging. As long as good cosmetic results can be achieved, surgical excision is quick, safe and effective treatment method for idiopathic granulomatous mastitis.
报告肉芽肿性乳腺炎患者的临床和病理特征以及手术治疗结果。
病例系列研究。
安卡拉肿瘤培训与研究医院,1999年至2003年。
回顾性分析16例接受手术完整切除且切缘无病变的肉芽肿性乳腺炎患者的数据。排除因疾病范围和大小而接受额外药物治疗或乳房切除术的患者。
患者诊断时的平均年龄为31.8岁(范围:22 - 45岁)。所有患者均通过手术获取的病理组织标本确诊。临床和影像学检查提示82.1%的患者患有乳腺癌。除1例患者切口处出现瘘管,再次接受手术治疗外,未观察到其他并发症,包括在中位随访期12.8个月(范围:4 - 30个月)内疾病复发。
尽管肉芽肿性乳腺炎是一种罕见的良性乳腺疾病,但在临床和影像学上通常类似乳腺癌,使得诊断困难且具有挑战性。只要能取得良好的美容效果,手术切除是特发性肉芽肿性乳腺炎快速、安全且有效的治疗方法。