利用串联质谱分析法分析边缘无形体主要表面蛋白1复合蛋白的组成。
Analysis of the Anaplasma marginale major surface protein 1 complex protein composition by tandem mass spectrometry.
作者信息
Macmillan Henriette, Brayton Kelly A, Palmer Guy H, McGuire Travis C, Munske Gerhard, Siems William F, Brown Wendy C
机构信息
Department of Veterinary Microbiology and Pathology, Washington State University, Pullman, WA 99164-7040, USA.
出版信息
J Bacteriol. 2006 Jul;188(13):4983-91. doi: 10.1128/JB.00170-06.
Abstract
The protective major surface protein 1 (MSP1) complex of Anaplasma marginale is a heteromer of MSP1a and MSP1b, encoded by a multigene family. The msp1beta sequences were highly conserved throughout infection. However, liquid chromatography-tandem mass spectrometry analysis identified only a single MSP1b protein, MSP1b1, within the MSP1 complex.
摘要
边缘无形体的保护性主要表面蛋白1（MSP1）复合物是由多基因家族编码的MSP1a和MSP1b的异源二聚体。在整个感染过程中，msp1beta序列高度保守。然而，液相色谱-串联质谱分析仅在MSP1复合物中鉴定出一种单一的MSP1b蛋白，即MSP1b1。
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