Sobol' M A, Kordium E L, Medina F Kh
Tsitol Genet. 2006 Jan-Feb;40(1):43-8.
The functions of the nucleolus responsible for the biosynthesis of ribosomes in altered gravity are still unclear. The location of nucleolar DNA both in control and simulated microgravity has been investigated using fluorescent and immunogold cytochemistry. We have determined the redistribution of rDNA in the nucleolar components accompanied by their ultrastructure changes. According to this the lowering of rDNA transcription level under simulated microgravity was supposed.
负责在重力改变条件下核糖体生物合成的核仁功能仍不清楚。已使用荧光和免疫金细胞化学方法研究了对照和模拟微重力条件下核仁DNA的定位。我们确定了核糖体DNA（rDNA）在核仁组分中的重新分布及其超微结构变化。据此推测在模拟微重力条件下rDNA转录水平降低。
